准分子激光术后3种屈光测量法的研究
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Analysis of three different refraction measurement after excimer laser corneal refractive surgery
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    摘要:

    目的:探讨准分子激光术后电脑验光仪-像差测量仪和综合验光仪3种屈光检查测量法准确性的研究及其影响因素-方法:随机抽取2008年12月~2009年1月于复旦大学附属眼耳鼻喉科医院视光门诊准分子激光手术的患者78例,154眼,患者术前及术后3个月(平均14.2周)的球镜量-散光量及轴向分别用3种检查法测量(均未予睫状肌麻痹),并将电脑验光仪和像差测量仪平均所得数据分别与综合验光仪所得数据进行比较-同时分别测量同一患者术前和术后的高阶像差-角膜曲率-角膜厚度等,比较同一眼术前及术后的差值,并将比较差异有统计学意义的球镜量-散光量及散光轴向分别与术前和术后的高阶像差-角膜曲率-角膜厚度等差值行单因素及多因素回归分析-结果:3种方法在准分子激光术前所测球镜量-散光量及散光轴向比较,只有电脑验光仪散光度数与综合验光仪散光度数比较差异有统计学意义(P < 0.05)-术后3个月电脑验光仪与综合验光仪球镜量-散光量及散光轴向比较P均 < 0.01-球镜量像差测量仪与综合验光仪比较P < 0.01,而散光量及轴向两者比较P > 0.05-术后影响因素单因素回归及多因素回归相关分析,电脑验光仪与综合验光仪球镜度差异与准分子激光术前及术后角膜曲率差值相关,回归系数为-0.073,P = 0.009,而像差测量仪与综合验光仪的球镜量差异则分别与术前及术后高阶像差C7(垂直彗差)和C12(四阶球差)及角膜曲率差值相关,回归系数分别为-0.475-0.489--0.004,P值分别为0.001-0.001-0.024,差异有统计学意义-结论:对于近视散光测量像差测量仪准确性要优于电脑验光,特别是准分子激光术后患者-同一眼在准分子激光术前术后测量准确性的差异主要与激光手术后角膜曲率及高阶像差的改变相关-

    Abstract:

    Objective:To investigate the refraction accuracy of three different measurements and their influencing factors after excimer laser corneal refractive surgery. Methods: Seventy-eight cases(154 eyes) performed with Excimer laser corneal refractive surgery from optometry clinic, the Eye Ear Nose and Throat Hospital, FuDan University were selected randomly from Dec 2008 to Jan 2009. Sphere,cylinder and cylinder axial of all the patients were measured three months(mean 14.2 weeks)before and after surgery by auto-refractomer wavefront analyzer and phoropter inspection(without cycloplegic). Higher-order aberration, corneal curvature and corneal thickness of every patient were also measured at the same time before and after surgery. Results: The cylinder of auto-refractor and phoropter were significantly different respectively(P < 0.05). Sphere, cylinder and cylinder axial of auto-refratomer and phoropter were significantly different (all P < 0.01) respectively. Sphere of wavefront analyzer and phoropter were statistician different (P < 0.01).The differences of sphere between auto-refratomer and phoropter were found to be related to the corneal curvature,(the regression coefficient is -0.07, P=0.009, P < 0.01). The differences of sphere between waverfront analyzer and phoropter were found to be respectively related to high order wave aberration (C7, C12 )and corneal curvature (The regression coefficient is -0.475, 0.489,-0.004,respectively, and P was 0.001, 0.001, 0.024, respectively). Conclusion: The accuracy of low order wave aberration is better than that of auto-refractomer in measuring refraction especially after surgery. The differences of which the accuracy of preoperative and postoperative measurement of the same eye with three instruments mainly relates to the changes of curvature of the cornea and higher-order aberrations after the excimer laser corneal refractive surgery.

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顾刘伟,袁志兰,周行涛.准分子激光术后3种屈光测量法的研究[J].南京医科大学学报(自然科学版),2011,(6):889-893

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  • 收稿日期:2010-11-17
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