儿童厌食症危险因素的1∶4配比病例对照研究
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江苏省教育厅科研基金资助(JH B05-25)


A 1∶4 matched case-control study on risk factors of anorexia in children
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    目的:探索儿童厌食症发生的危险因素-方法:以社区为基础的1∶4配比病例对照研究,结合问卷调查和血清维生素A测定,采用条件Logistic回归模型分析危险因素-结果:多因素条件Logistic回归分析显示,儿童进食不定量(OR=1.500,95%CI=1.071~2.101,P = 0.018)-挑食偏食(OR=1.780,95%CI=1.267~2.501,P = 0.001)-家长强制儿童进食(OR=2.133,95%CI=1.491~3.054,P < 0.001)-患有消化道疾病(OR=3.106,95%CI= 1.955~4.933,P < 0.001)-近2周患有呼吸道感染(OR=1.669,95%CI=1.112~2.513,P = 0.013)-出生后喂养困难(OR=1.946,95%CI=1.284~2.950,P = 0.002)以及血维生素A缺乏(OR=3.222,95%CI=1.660~6.256,P = 0.001)与厌食症存在显著关联-结论:应该纠正儿童不良饮食习惯,普及科学知识以及适时补充维生素A,以减少儿童厌食症的发生-

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    Objective: To explore risk factors for anorexia in children. Methods: A community-based 1:4 matched case-control study was conducted using questionnaire survey and vitamin A detection. Conditional logistic regression was used to estimate odds ratio. Results: Multivariate conditional Logistic regression analysis showed that Feeding without ration (OR=1.500,95%CI=1.071~2.101,P = 0.018),Partiality for a particular kind of food(OR=1.780,95%CI=1.267~2.501,P = 0.001),Be forced to feed by paterfamilias(OR=2.133,95%CI= 1.491~3.054,P < 0.001),Be ill with digestive diseases(OR=3.106,95%CI=1.955~4.933,P < 0.001),Be ill with respiratory infection in recent two weeks(OR=1.669,95%CI=1.112~2.513,P = 0.013),Feeding hardly just after birth(OR=1.946,95CI=1.284~2.950,P = 0.002) and Be lack of vitamin A (OR=3.222,95%CI=1.660~6.256,P = 0.001) are associated significantly with anorexia in children. Conclusion: Prevention and control measurements should be focused on the bad habits of children,nutritional knowledge of their parents and timely vitamin A rich foods intake to reduce the risk of anorexia.

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刘 伶,陆晓梅,徐济达,张 娟,王 嵘,敖淑清.儿童厌食症危险因素的1∶4配比病例对照研究[J].南京医科大学学报(自然科学版),2011,(12):1879-1881

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  • 收稿日期:2011-09-17
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