不同氟暴露男性人群不育情况比较与分析
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贵州省科技厅基金(黔科合J字[2009]2322号);贵州省科技厅?遵义医学院?遵义市科技局联合基金(黔科合J字LKZ[2010]32号);贵州省卫生厅优秀医学青年科技人才基金(gzwkj2010-2-001)


Comparison and analysis of male infertility in different fluorine exposure populations
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    摘要:

    目的:探讨不同氟暴露情况下男性人群不育情况的差异-方法:对高氟区组94例和低氟区组114例男性人群与氟暴露相关的生活居住环境-饮食情况-生育情况等进行调查,并分析比较两组人群生活习惯-氟暴露情况-生育情况等的差异-结果:高氟区组在经常用煤-喜爱喝茶-氟斑牙程度-不育率等方面显著高于低氟区组(P < 0.05),而在炉灶改良-使用含氟牙膏等方面显著低于低氟区组(P < 0.05);多因素Logistic回归显示“调查对象来自高氟区”和“使用未改良炉灶”对男性不育的影响有统计学意义(P < 0.05)-结论:高氟区组在煤烟型氟暴露和不育情况方面均比低氟区组更严重,提示长期高氟暴露是不育的危险因素,可致男性人群不育的风险升高-

    Abstract:

    Objective:To explore the differences of male infertility in different fluorine exposure populations. Methods:Villages were divided into high-fluorine-region group (n = 94) and low-fluorine-region group (n = 114). Their living situations,diet,fertility and other fluorine exposure related aspects were collected and compared between two groups. Results:Compared with low-fluorine-region group,it was significantly higher in the frequency of using coal and drinking tea,degree of dental fluorosis,and rate of infertility(P < 0.05),while significantly lower in the use of improved stoves and fluorine toothpaste in high-fluorine-region group(P < 0.05). The factors of “survey objects from high-fluorine region” and “stove unimprovement” significantly affected on male infertility in multiple Logistic regression(P < 0.05). Conclusion:Coal-burning-type fluorine exposure and the incidence rate of infertility in high-fluorine-region group was more serious than low-fluorine-region group,which suggested that long-term fluorine exposure was a risk factor of infertility,which could increase the risk of male infertility.

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石修权,王海燕,余 静,王克跃,周远忠.不同氟暴露男性人群不育情况比较与分析[J].南京医科大学学报(自然科学版),2012,(7):1024-1028

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  • 收稿日期:2012-02-13
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