气相色谱/质谱联用测定室内灰尘中邻苯二甲酸酯
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国家自然科学基金面上项目(81072268);江苏省自然科学基金面上项目(BK2010535);江苏省博士后基金(1001017C);江苏高校优势学科建设工程资助项目


Determination of phthalate esters in house dust by gas chromatography/mass spectrometry
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    摘要:

    目的:建立气相色谱/质谱联用测定室尘中7种常见邻苯二甲酸酯(phthalate esters,PEs)的分析方法-方法:用吸尘器采集室尘,用正己烷超声提取室尘中的PEs,浓缩后用正己烷定容至0.2 ml,气相色谱/质谱仪分析测定-结果:7种PEs 22 min内彼此完全分离,在5~2 000 ng/ml范围内线性关系良好,相关系数r均 > 0.998,相对标准偏差为5.66%~18.03%,加标回收率为87.73%~110.63%-结论:该方法测定室尘中PEs经济-快速-简便-灵敏,重现性好,符合大样本量室尘样品中PEs的测定要求-

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    Objective:To establish a simple method for determination of 7 phthalate esters (PEs) by gas chromatography/mass spectrometry (GC/MS). Methods:Vacuum cleaner was used for gathering the house dust,and n-hexane was added and extraction was performed in an ultrasonic bath. The supernatant was concentrated and then added with n-hexane to 0.2 ml. PEs were determined by GC/MS. Results:Seven PEs had highly efficient separation within 22 minutes and showed good linearity within 5~2 000 ng/ml range with correlation coefficients all beyond 0.998. The relative standard deviations were 5.66%~18.03%,and the recoveries were 87.73%~110.63%. Conclusion:This method was a economic,fast,simple,sensitive and reproducible enough for settled-dust PEs measurements in house dust with large sample size.

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陆晓梅,张 绮,张晓玲,董海峰,张正东,王炳玲.气相色谱/质谱联用测定室内灰尘中邻苯二甲酸酯[J].南京医科大学学报(自然科学版),2012,(7):1038-1042

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  • 收稿日期:2012-03-12
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