持续性操作测验在学龄前儿童注意缺陷多动障碍诊断中应用价值探讨
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国家自然科学基金资助(30801255);江苏省医学重点人才资助(RC2011022);南京市医学科技发展项目(201108007);南京医科大学科技发展基金(2010NJMU0024)


Clinical application of K-CPT on preschool children with attention deficit hyperactivity disorder
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    目的:探讨4~5岁儿童注意力持续测试软件(Conners’ kiddie continuous performance test,K-CPT)在诊断学龄前儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)中的临床应用价值-方法:以美国精神障碍诊断和统计手册第4版(DSM-IV)为诊断标准,对41例临床诊断ADHD的儿童,进行Conners’父母用简明症状问卷(parent symptom questionnaire,PSQ)调查和K-CPT评估-结果:K-CPT评估结果与DSM-IV诊断标准比较,在ADHD检出率方面无显著性差异(P > 0.05)-K-CPT诊断学龄前ADHD的灵敏度为73.3%,特异度为81.8%,假阳性率为18.2%,假阴性率为26.7%,符合率为75.7%,Kappa值为0.470(P < 0.001),K-CPT与金标准之间存在中度一致性-K-CPT和PSQ在患儿阳性检出率方面,差异均无显著性(P > 0.05)-结论:K-CPT测试结果可作为客观诊断指标,用于学龄前ADHD的协助诊断-

    Abstract:

    Objective:To explore the clinical application of Conners’ kiddie continuous performance test (K-CPT) on diagnosis in preschool children with attention deficit hyperactivity(ADHD). Methods:Using the diagnostic and statistical manual of Mental disorders (DSM-IV) as a gold standard,K-CPT and parent symptom questionnaire(PSQ) were tested in 41 cases of preschool children with ADHD and evaluated. Results:Compared with DSM-IV,the sensitivity for K-CPT in diagnosing ADHD reached 73.3%,specificity for K-CPT was 81.8%,the false negative rate was 26.7%,and the false positive rate was 18.2%. The coincidence rate amounted 75.7%. The value of kappa was 0.470 (P < 0.001). There is no significant difference(P > 0.05) in the detection rate of K-CPT and PSQ. Discussion:K-CPT could be used as an objective diagnostic tool and applied in diagnosis of preschool ADHD.

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谈晓轶,池 霞,梁 沂,徐亚琴,王 丽,周 影,张 蕾.持续性操作测验在学龄前儿童注意缺陷多动障碍诊断中应用价值探讨[J].南京医科大学学报(自然科学版),2012,(12):1727-1730

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  • 收稿日期:2012-06-03
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  • 在线发布日期: 2013-01-09
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