Objective: To study the efficacy of different use of oxytocin during elective cesarean section. Methods:A total of 160 samples of Anaesthesiologists Ⅰ and Ⅱ subjects undergoing cesarean delivery were randomly divided into four groups. Following fetal extraction,the uterus was injected 20 U oxytocin. Women in the A group received 20 U of oxytocin intravenously within 30 seconds. The B group received 10 U of oxytocin within 30 seconds. The C group received 5 U of oxytocin within 30 seconds followed by an infusion of 5 U/h for 2 hours. The D group received 2 U of oxytocin within 30 seconds followed by an infusion of 10 U/h for 2 hours. We detected ECG,NBP,SpO2, hemodynamics and postoperative vaginal bleeding with 24 hours,uterine contractility, and adverse effects after administration of oxytocin,the serum oxytocin concentration at the beginning of injection,10,30,60 min. Results:After the administration of oxytocin,the MAP in the A and B groups decreased,but the heart rate increased. The incidence of vomiting and nausea was higher in the group A. The serum oxytocin concentration was significantly increased in the group A,B and C,and then decreased. Compared among groups,the serum oxytocin concentration of the group A,B,C and D were decreased by turns. There was no difference among the groups in the vaginal bleeding volume and the uterine contractility. Conclusion:Low dose of oxytocin followed by an infusion could stable the hemodynamics of women during the elective cesarean section and decreased the adverse effects.