Objective:To explore the epidemic characteristics of infective diarrhea disease in Jiangsu province,and to provide scientific basis for effective strategy for general control and monitoring of diarrhea disease. Methods:The epidemiological characteristics and etiologic characteristic of infective diarrhea disease in Jiangsu from 2004 to 2011 were analyzed. A total of 246 hospital of county and above level were investigated to understand the capability of breadboard detection. Results:The incidence of infective diarrhea disease in Jiangsu has been decreasing by years from 2004 to 2010,the incidence bounced in 2011. The average incidence rate was 43.79/100 000. There was a visible supernumerary tendency of constituent ratio in other diarrhea disease. The typical and aestival peak was observed in summer,but there was a regularity and specificity which “V” type distribution was observed from August to October. With occupational distribution,peasants,students,workers and scattered children were the major infected population. Piecemeal decrease of incidence rate was following with aetatis increase. The incidence rate of male was higher than female.The incidence rate and capability of breadboard detection in southern part were higher than central region,and central region were higher than north part. Conclusion:The incidence of infective diarrhea disease has been well controlled. There was a visible supernumerary tendency in epidemiological characteristics. Further step should be taken for the capability of laboratory,diagnose and positive report.