非限制性人工椎间盘假体植入三维有限元模型的建立
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南京医科大学科技发展基金面上项目(2010NJMU059);南京市医学科技发展项目(QYK11174);南京市卫生青年人才培养工程


Constructing a three-dimensional finite element model of non-constrained artificial disc replacement
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    摘要:

    目的:建立非限制性人工椎间盘假体(NAD)及腰椎L4~L5活动节段高精度三维有限元(FE)模型,拟为生物力学实验研究提供标准数学模型。方法:在Auto CAD中设计NAD假体,基于CT数据通过Mimics建立腰椎L4~L5节段三维模型,将NAD模型放置于L4~L5椎间盘,数据导入Abaqus采用有限元装配技术转换成有限元模型。观察NAD置换后FE模型的模拟单元-节点及构成组件。采用轴向负荷400 N以模拟L4~L5节段正常的中立位负荷,采用轴向负荷400 N及10 N-m模拟后伸负荷,验证所建立模型的科学性。结果:建立了非限制性人工椎间盘假体放置于腰椎L4~L5活动节段高精度三维有限元模型,包括:腰椎L4~L5活动节段FE模型34 123个节点及162 858个单元,其中椎体161 679个四面体单元,椎间盘-终板共1 053个六面体单元,韧带-关节囊-纤维共126个Link单元;NAD的FE模型1 583个节点及4 927个单元,其中终板共1 053个六面体单元,髓核3 724个六面体单元。力学测试显示中立位负荷及后伸负荷时所建立FE模型力学分布与现有结果一致。结论:通过计算机辅助设计可以自动化程度较高的方法建立高精度NAD假体有限元模型,Mimics通过基于阈值算法及参数化建模提供精确腰椎活动节段模型,两者可以基于有限元装配技术转换成有限元模型,该模型可用于脊柱生物力学的进一步研究。

    Abstract:

    Objective:To construct a three-dimensional finite element(FE) model of non-constrained artificial disc (NAD) replacement and lumbar vertebrae L4~L5 segment as the standard digital model for further biomechanical research. Methods:The NAD FE model was designed by using Auto CAD and it was combined with lumbar segment FE model in aforementioned part one by Abaqus software. The L4~L5 model was validated by Force 1,a 400 N axial load which was made up of four 100 N stress force,then Force 2 which was composed of 400 N axial load and 10 N-m extension bending moment. Results:L4~L5 segment model was consisted of 33,976 nodes and 162,858 elements. Centrum was consisted of 161,679 tetrahedron elements. Endplate was consisted of 1,053 hexahedral elements. Ligament,articular capsule and fiber were consisted of 126 Link elements. The NAD model was consisted of 11,583 nodes and 44,927 elements. Endplate and nucleus pulposus was consisted of 1,053 and 3,724 hexahedral elements,respectively. The results of load test showed that the model of NAD and L4~L5 segment had good effect of visual and mathematics. Conclusion:Based on mimics software and CAD methods,the 3D FE model of lumbar motion segment and artificial disc can be constructed automatically with excellent simulation results. Mimics can provide precise model through calculation based on threshold and parameterization modeling. The implanted L4~L5 segment can be used for further biomechanical research of lumbar spine.

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郑圣鼐,韩廷成,姚庆强,王黎明,金成哲,唐 城,胡文浩,魏 波,杜小涛.非限制性人工椎间盘假体植入三维有限元模型的建立[J].南京医科大学学报(自然科学版),2013,(8):1155-1160

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  • 收稿日期:2012-06-02
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  • 在线发布日期: 2013-07-30
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