标化的肾肿瘤患者肾体积与肾功能的相关性
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江苏高校优势学科建设工程资助项目


Correlation between renal volume normalized by BSA and renal function in patients with renal tumors
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    目的:在肾肿瘤患者增强CT(computed tomography)图像上,探讨体表面积(body surface area,BSA)标化后的肾体积与肾功能的相关性-方法:34例肾肿瘤患者于术前1周内均行中腹部增强CT扫描及核素肾动态显像检查-基于动脉期图像测量剔除肿瘤后残余双肾体积,包括肾皮质体积(renal cortical volume,RCV)和肾髓质体积(renal medullary volume,RMV)-肾实质体积(renal parenchymal volume,RPV)为RCV与RMV两者之和-以核素肾动态显像测定的肾小球滤过率(glomerular filtration rate,GFR)为参照标准,将RPV-RCV和BSA标化后的RPV(RPVBSA=RPV/BSA)-RCV(RCVBSA=RCV/BSA)与GFR分别行相关性分析-结果:RPV和RCV与GFR呈中度正相关,r值分别为0.474(P = 0.005)和0.448(P = 0.008);RPVBSA和RCVBSA与GFR呈中高度正相关,r值分别为0.659(P < 0.001)和0.627(P < 0.001)-结论:基于增强CT动脉期图像测量的RPV和RCV可以反映肾功能,RPVBSA和RCVBSA能更好地对肾肿瘤患者术前肾功能进行评估-

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    Objective:To assess the correlation between renal volume measured on contrast-enhanced CT images normalized by BSA (body surface area) and renal function in patients with renal tumors. Methods:Thirty-four patients with renal tumors underwent abdominal contrast-enhanced CT and radionuclide renography within one week before surgery. Residual bilateral renal cortical volume (RCV) and renal medullary volume (RMV) on arterial phase images were measured by a semiautomatic software. Renal parenchymal volume (RPV) was the sum of RCV and RMV. Glomerular filtration rate (GFR) measured by radionuclide renography was considered as the reference standard. RPV,RCV,RPV normalized by BSA(RPVBSA=RPV/BSA),and RCV normalized by BSA(RCVBSA=RCV/BSA) were correlated with GFR using the Pearson correlation coefficient,respectively. Results:The correlation between RPV / RCV and GFR presented r = 0.474,P = 0.005 and r = 0.448,P = 0.008,respectively. RPVBSA and RCVBSA had a higher degree of correlation (r = 0.659,P < 0.001 and r = 0.627,P < 0.001) with GFR. Conclusion:RPV and RCV measured on arterial phase images could estimate renal function,while RPVBSA and RCVBSA in patients with renal tumors had a better correlation with renal function before surgery.

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刘王琰,徐 怡,唐立钧,朱晓梅,祝因苏,杨冠羽,施海彬.标化的肾肿瘤患者肾体积与肾功能的相关性[J].南京医科大学学报(自然科学版),2014,(2):224-229

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  • 收稿日期:2013-08-23
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  • 在线发布日期: 2014-03-03
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