Abstract:Objective:To evaluate the effect of early minimal feeding on low birth weight infants of China. Methods:We searched CBM,CAJ,Wanfang and CQVIP databases using keywords since databses established. Also we searched MEDLINE for Chinese papers. Results:Tweenty-four researches were included.(1)Time of parenteral nutrition in early minimal feeding group is shorter than control group WMD= -5.73;95%CI=[-6.68,-4.78];P < 0.00001;(2)Weight gain per day in early minimal feeding group is more than control group WMD= 3.64;95%CI=[1.85,5.44];P < 0.0001;(3)Time of returning to birth weight in early minimal feeding group is shorter control group WMD=-2.59;95%CI=[-3.35,-1.83];P < 0.00001;(4)Incidence of NEC in early minimal feeding group doesn’t show statistical significance compared with control group OR= 0.70;95%CI=[0.35,1.41];P=0.32;(5)Incidence of feeding intolerance is lower than control group OR= 0.38;95%CI=[0.24,0.60];P < 0.0001;(6)Incidence of hypoglycemia is lower than control group OR= 0.19;95%CI=[0.10,0.35];P < 0.00001. Conclusion:The early minimal feeding group has an advantage over control group in time of parenteral nutrition,weight gain,time of returning to birth weight,incidence of NEC,feeding intolerance and hypoglycemia.