Abstract:Objective: To study the preparation and properties of gelatin-graft-polyaniline(GP) hydrogel. Methods: GP was synthesized by direct doping technique, and camphor sulfonic acid(CSA) was used as dopant. The copolymer was dissolved in water and then cross-linked by EDC. The morphology and chemical feature, swelling ratios, dissolubility, biocompatibility and conductivity of GP hydrogels(GPH) were observed. Results: GPH had good conductivities (1×10-4~10-3 S/cm). The electrical property was enhanced with the content of polyaniline. Nonetheless, when the amount of polyaniline improved to a certain degree, the solubility was greatly reduced and swelling ratio was increased at the same time. Conclusion: GPH is a biodegradable conductive material and has great application prospects in tissue engineering.