针刺疗法治疗乳腺癌术后潮热短期和中期有效性的Meta分析
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江苏省中医药科技项目(YB2017089);江苏省“六大人才高峰”项目(2016-WSN-094)


Short⁃and medium⁃clinical effect of acupuncture in treating hot flashes in patients with breast cancer: a meta⁃analysis
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    目的:运用循证医学的方法,对针刺疗法治疗乳腺癌术后潮热短期和中期有效性进行Meta分析。方法:收集 2017年6月30日以前 CNKI、CBM、维普、万方、PubMed 数据库针刺疗法治疗乳腺癌术后潮热的临床试验资料,用 Cochrane 系统评价方法对文章进行质量评分,利用Revman5.3软件对多个研究结果的总体效应进行Meta分析,并进行异质性评价。结果:共纳入6篇文献,Meta分析结果示治疗3个月(SMD:-0.36,95%CI:-0.61~-0.10)和6个月(SMD:-0.41,95%CI :-0.64~-0.18)的随访结果都表明针刺组患者的潮热症状改善优于对照组,两组比较差异有统计学意义(P=0.006,P=0.000 5)。结论:在研究设计较完善的临床研究中,针刺对于乳腺癌术后潮热症状改善的短期和中期效果优于对照组。

    Abstract:

    Objective:To evaluate the short and medium-clinical effect of acupuncture therapy in treating hot flashes in patients with breast cancer by meta-analysis. Methods: This systematic research analyzed all randomized controlled trials (RCTs) relating with the effects of acupuncture treatment for hot flashes of breast cancer patients in the CNKI,CBM,VIP,Wanfang and PubMed (30th June 2017 ago). The quality of RCTs was assessed by Cochrane systematic review. Multiple overall effects of results were analyzed with meta-analysis,and evaluated systematically by RevMan5.3 software. The heterogeneity was evaluated. Results: In the follow-up visit of 3 months (SMD=-0.36,95%CI: -0.61~-0.10) and 6 months (SMD=-0.41,95%CI: -0.64~-0.18),acupuncture improved the syndrome systematically (P=0.006,P=0.000 5,respectively). Conclusion: The results of clinical researches with high study quality show that acupuncture treatment can significantly improve the syndrome of hot flashes in short- and medium-term in breast cancer patient.

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卢 静,高 岑,陈 欢,查小明,张朝晖.针刺疗法治疗乳腺癌术后潮热短期和中期有效性的Meta分析[J].南京医科大学学报(自然科学版),2018,(11):1533-1539

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  • 收稿日期:2018-06-29
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  • 在线发布日期: 2018-12-03
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