空腹血糖对缺血性脑卒中患者脑血管狭窄程度的影响
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国家重点研发计划(2018YFC1314901);国家自然科学基金青年基金(81600001);江苏省自然科学基金青年基金(BK20141026);江苏省医学重点人才(ZDRCA2016005);江苏省科技计划项目(BE2016002-4);南京市科技计划项目(201608003)


Effects of fasting plasma glucose on the severity of cerebrovascular stenosis in ischemic stroke patients
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    摘要:

    目的:探讨空腹血糖(fasting plasma glucose,FPG)对缺血性脑卒中患者脑血管狭窄程度的影响。方法:回顾性分析缺血性脑卒中患者307例,按FPG水平分为3组,对患者的实验室及影像学资料进行分析。结果:随着FPG增加,脑血管狭窄支数、狭窄程度均增加。年龄<60岁的患者,FPG 5.6~7.0 mmol/L组及FPG>7.0 mmol/L组的脑血管狭窄均重于FPG<5.6 mmol/L组;年龄≥60岁的患者,FPG>7.0 mmol/L组的脑血管狭窄较FPG<5.6 mmol/L组严重。结论:缺血性脑卒中患者脑血管的狭窄程度随着FPG增加而增加;<60岁的患者FPG>5.6 mmol/L或≥60岁的患者FPG>7.0 mmol/L,其脑血管的狭窄程度较同龄FPG<5.6 mmol/L者严重。

    Abstract:

    Objective:To investigate the effect of fasting plasma glucose(FPG) on the severity of cerebrovascular stenosis in patients with ischemic stroke. Methods:Three hundred and seven patients with ischemic stroke were divided into three groups according to the level of FPG. The clinical features and imaging data of patients were analyzed. Results:With the increase of FPG,the number of diseased vessel,the severity of cerebrovascular stenosis were increased. In patients with age< 60 years,the cerebrovascular stenosis in FPG 5.6-7.0 mmol/L group and FPG > 7.0 mmol/L group was severe than that in FPG < 5.6 mmol/L group. And in patierts with age≥60 years the stenosis in FPG > 7.0 mmol/L group were more serious than that in FPG < 5.6 mmol/L group. Conclusion:Stenosis of cerebrovascular in ischemic stroke increased along with the increase of FPG. The vascular stenosis in patients less than 60 years old with FPG > 5.6 mmol/L or over 60 years old with FPG > 7.0 mmol/L is more serious than that in patients with FPG < 5.6 mmol/L.

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周 玮,卢 姗,杨 洁,阚敬保,沈歌前,刘 云.空腹血糖对缺血性脑卒中患者脑血管狭窄程度的影响[J].南京医科大学学报(自然科学版),2019,(2):228-231

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  • 收稿日期:2018-07-19
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  • 在线发布日期: 2019-03-06
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