Objective:To evaluate the efficacy and safety of pituitrin injection combined with hysteroscopy and suction curettage for typeⅠcesarean scar pregnancy(CSP). Methods:From November 2016 to July 2018,21 patients(the experimental group)with typeⅠ CSP in the First Affiliated Hospital of Nanjing Medical University were treated with pituitrin injection combined with hysteroscopic suction curettage,while 83 patients(the control group)with typeⅠCSP were treated with uterine artery embolization(UAE)followed by suction curettage as first-line therapy. The clinical data were analyzed with statistics to compare the efficacy and safety between the two groups. Results:The time of postoperative vaginal bleeding,postoperative hospitalization and the total hospitalization duration was shorter in the experimental group(P < 0.05).The total hospitalization expenses and the occurrence rate of adverse reactions were lower in the experimental group than the control group(P < 0.05).There was no significant difference in the treatment success rate,the average operative duration,the intraoperative blood loss,the time when serum β-HCG return to the normal range and the recovery time of menstruation after hospital discharge between the two groups(P > 0.05). Conclusion:For TypeⅠCSP,both UAE followed by suction curettage and pituitrin injection combined with hysteroscopic suction curettage appear to be nice options. However pituitrin injection combined with hysteroscopic suction curettage possesses an apparent advantage over UAE followed by suction curettage. It may be a priority option for typeⅠCSP.