Conventional right ventricular apical pacing is deleterious to heart function and as a result,mortality increases. His bundle pacing utilizes the special conduction system of the heart and activates the double ventricular chamber simultaneously that models physiological pacing model efficiently. Different clinical studies have demonstrated that the feasibility,safety and effectiveness of applying His bundle pacing. Left bundle branch area pacing is a novel method proposed in the further exploration of physiological pacing,with the merits of overcoming the shortcomings of His bundle pacing,such as low success rate,low sensitivity and high threshold. This article provides a comprehensive review over the most up-to-date research progress of clinical application using His bundle pacing and Left bundle branch area pacing.