基于3D⁃MATRIX序列的压缩感知技术在膝关节成像中的临床应用价值
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江苏省医学重点人才基金项目(ZDRCB2016 003)


A localization system for multiple magnetic targets based on magnetic sensor scanning detection
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    摘要:

    目的:探讨基于3D可调制翻转角超长回波链回聚脉冲成像(three-dimensional modulated flip angles technique in refocusing imaging with extended echo train,3D-MATRIX)的压缩感知(compressed sensing,CS)技术在膝关节中的临床应用价值。方法:对26例患者的26个膝关节均采用CS-3D-MATRIX(CS-3D)和3D-MATRIX(传统3D)扫描。对两组图像的伪影(0~4)、锐利度(0~4)和图像综合质量(0~4)进行评分;分析两组膝关节图像中的软骨、肌肉、滑膜液、骨髓腔和前交叉韧带的信噪比(signal to noise ratio,SNR),骨髓腔-软骨、骨髓腔-滑膜液、软骨-肌肉、滑膜液-软骨、滑膜液-前交叉韧带的对比噪声比(contrast to noise ratio,CNR),并进行统计学分析。结果:两序列图像伪影和总体图像质量无明显差异,CS-3D图像锐利度略低于传统3D[(3.39±0.50)分 vs. (3.79±0.42)分,P=0.008]。与传统3D相比,除骨髓腔和前交叉韧带外,CS-3D获得的SNR均升高;CS-3D滑膜液-前交叉韧带、滑膜液与软骨的CNR显著提高,其他组织的CNR值略有升高但无统计学差异。CS-3D扫描时间较传统3D减少了46%。结论:与传统3D扫描序列相比,CS-3D-MATRIX序列的扫描时间缩短,但图像质量无明显差异。

    Abstract:

    Objective:A localization system for multiple magnetic targets based on magnetic sensor rotation detection was studied,which was aimed at realizing human multiple capsule endoscopy positioning and nano-magnetic drug testing. Methods:A three-axis tunneling magnetoresistive sensor was used to make a circular motion near the magnetic source. Three sets of magnetic signals were acquired and transferred by three-dimensional coordinates. The position of the permanent magnet was solved using a positioning algorithm. Results:Through the preparation of LabVIEW PC program,the trajectory of two magnetic target tracking and motion curve storage and playback were achieved. Conclusion:The detection system has the advantages of good real-time,high precision and low cost,it has the potential application value for the positioning of multiple capsules in the human body and the detection of nano-magnetic drugs.

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宋春娟,祁 良,朱晓梅,唐立钧.基于3D⁃MATRIX序列的压缩感知技术在膝关节成像中的临床应用价值[J].南京医科大学学报(自然科学版),2019,(10):1529-1532

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  • 收稿日期:2019-05-29
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  • 在线发布日期: 2019-11-01
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