Magnetic resonance molecular imaging is an important method for early diagnosis of tumors. It has broad prospects for its advantages of non-invasive，non-ionizing radiation and high soft tissue resolution. The design and development of magnetic resonance tumor-targeted molecular probes are keys to tumor molecular imaging. Different molecular recognition systems are used to develop a variety of specific targeted affinity probes，and to achieve the purpose of tumor genes and characteristic molecules imaging. In this paper，the latest progresses of magnetic resonance tumor molecular probes in recent years are reviewed.