Objective：This study aims to compare the early results of total hip arthroplasty（THA）by direct anterior approach（DAA），lateral approach（DLA） and posterior approach（PA）. Methods：A total of 22 patients（8 males and 14 females）who underwent total hip arthroplasty using DAA from September 2018 to September 2019 were retrospectively analyzed. Of the patients who underwent total hip arthroplasty using DLA and PA during the same period，22 were matched according to age，BMI，etiology，and severity. The operation time，incision length，postoperative 3-day continuous pain score（VAS），phosphokinase（CK），C-reactive protein（CRP），hemoglobin，blood loss，postoperative 1-month and 3-month Harris scores，prosthesis position and postoperative complications in the three groups were statistically analyzed. Results：The VAS on the first and second day after operation in DAA group was lower than that in DLA group，and the difference had statistical significance. The Harris score at 1 month after operation in DAA group was higher than that in DLA and PA groups（P < 0.05）. The operation time DAA was（90.91 ± 18.55）min，the difference was statistically significant compared with the other two groups（P < 0.05）. Conclusion：Compared with the traditional direct lateral approach and posterior approach，the direct anterior approach has the advantages of less postoperative pain and faster short-term rehabilitation.