矢状缝早闭症的诊疗进展
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南京市医学科技发展基金(YKK16189)


Progress in diagnosis and treatment of sagittal synostosis
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    摘要:

    矢状缝早闭症(sagittal synostosis,SS)是儿童最常见的非综合征型颅缝早闭,可表现出语言运动发育迟缓,颅内压升高、认知功能障碍、精神活动异常、癫痫发作等症状。目前主要的诊断方法是体格检查、临床表现及影像学检查。SS的主要治疗方式是手术治疗,根据患儿不同的年龄、颅缝闭合的程度及颅压增高导致小脑扁桃体下疝的程度等选择手术方式,不同手术方式也颇受争议。文章旨在总结分析SS的发病机制、诊断依据、治疗方法及术前术后发育评估,以期在SS未来的诊断及治疗方面提供有效依据。

    Abstract:

    Sagittal synostosis(SS)is the most common non-syndromic craniosynostosis in children,manifesting itself in language-motor development delay,intracranial pressure increase,cognitive dysfunction,abnormal mental activities and seizures. At present,the main diagnostic methods are physical examinations,clinical manifestations and imaging examinations,and the main treatment of SS is operative treatment currently. However,there are many surgical methods selected in terms of different ages of children,degree of cranial suture closure,and degree of cerebellar tonsillar hernia caused by increased cranial pressure. Meanwhile,controversy persists in choosing surgical treatments. The purpose of this review is to investigate the pathogenesis,diagnostic standards,therapeutics of SS,and evaluate preoperative and postoperative neurodevelopment of SS,which can provide convincing evidence for future diagnosis and treatment of SS.

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王 静,颜 青,王 刚.矢状缝早闭症的诊疗进展[J].南京医科大学学报(自然科学版),2020,(9):1391-1397

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  • 收稿日期:2019-09-23
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  • 在线发布日期: 2020-09-30
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