Objective：The epidemiological characteristics of covid-19 in Nanjing were analyzed to provide theoretical reference for the prevention and control of covid-19 in this region. Methods：A total of 93 confirmed cases of covid-19 admitted to the isolation ward of Tangshan Branch of Nanjing Second Hospital（Nanjing Public Health Medical Center）from January 23，2020 to March 8，2020 were collected for epidemiological analysis. Results：Nanjing is the city with the largest number of local COVID-19 confirmed cases in Jiangsu province. The confirmed cases are mainly distributed in the main urban area，with 55% of males，mostly aged 18~45 years old，and the occupations are employees，retirees，and industrial and commercial practitioners are the mainstay，with light and common types accounting for the vast majority，accounting for 97.5% of the total confirmed cases. In the early stage of the epidemic，imports were mainly domestic，of which 37 cases were imported from Hubei epidemic area，accounting for 82% of imported confirmed cases. In the middle of the outbreak，local cases were mainly renewed on the basis of imported cases，and initial control period of local outbreak was from February19 to March 8，2020. The cure rate of local COVID-19 in Nanjing was 100%，and there were no deaths or cases of occupational exposure among medical workers. Conclusion：The confirmed COVID-19 cases in Nanjing are mainly distributed in the main urban and people are generally susceptible，the epidemic situation was in transition from imported to local renewal，and with high cure rate，no deaths and health workers infected were due to occupational exposure.