Syphilis infection and related factors among men who have sex with men from 2011 to 2017 in Nanjing
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摘要:
目的：分析本地区男男性行为（men who have sex with men，MSM）人群梅毒感染状况及影响因素。方法：通过同伴推动法和滚雪球法招募3 043例16周岁以上MSM人群，采用χ2检验和非条件多因素Logistic回归分析方法，分析影响MSM人群梅毒感染的影响因素。结果：MSM人群中梅毒感染率为14.7%，感染率随年龄增长而显著增加；文化程度低、离异/丧偶者感染率高，差异有统计学意义（P < 0.05）。年龄、文化程度、是否再婚或者同居对梅毒感染有显著影响。与梅毒感染阴性的MSM相比，感染人类免疫缺陷病毒的风险在梅毒感染者中显著增加（OR=2.48，95%CI：1.81~3.40）。结论：MSM人群中梅毒感染率高，梅毒感染者中人类免疫缺陷病毒感染风险高，应制定梅毒、艾滋病综合防治策略，以进一步提高MSM人群梅毒和艾滋病防制的效果。
Abstract:
Objective：This study aims to analyze syphilis infection and its risk factors among men who have sex with men（MSM）. Methods：Altogether 3 043 MSMs aged 16 and above were recruited by respondent driven sampling and snowball sampling method. Multivariate unconditional logistic regression was used to analyze factors associated with syphilis infection. Results：The prevalence of syphilis infection was 14.7% among 3 043 MSMs，and increased with age. Those with lower educational level and divorce/widowhood had a higher prevalence，with significant differences（P < 0.05）. Logistic regression analysis showed age，educational level，and marriage status had significant relationship with syphilis infection. The risk for human immunodeficiency virus（HIV） infection increased in MSMs with syphilis infection（OR=2.48，95%CI：1.81-3.40）. Conclusion：The syphilis infection is high in MSMs，and the risk of HIV infection is higher in those with syphilis infection. Comprehensive strategies should be developed to further improve the effect of syphilis and HIV prevention and control in MSMs.
