Objective：This study aims to explore the short-term effect of sublingual allergen-specific immunotherapy in children with allergic rhinitis. Methods：There were 71 subjects of 3-15 years old with allergic rhinitis who were sensitized to dermatophagoides farinae. They were treated with standardized sublingual dermatophagoides farinae immunotherapy drops. Then the short-term effects of the treatment were evaluated by comparing the outcome scores including the total rhinitis symptom scores，total medication scores and visual analogue scale（VAS）before and after the treatment for every three months until a year. Results：Total rhinitis symptom scores，total medication scores and VAS were all declined in 3 months，6 months，9 months and 12 months after the treatment compared with those before the treatment. Meanwhile，the three scores were all declined in 6 months and 9 months compared with those in 3 months and 6 months，respectively. Total rhinitis symptom scores and VAS were both declined while no difference was shown in total medication scores in 12 months compared with those in 9 months. Conclusion：In the short term，sublingual dermatophagoides farinae immunotherapy is an effective way to treat 3-15 years old children with allergic rhinitis who are sensitized to dermatophagoides farina，which can take effect in 3 months after the treatment，and becomes more and more effective in 6 month，9 months and 12 months.