江苏某戒毒所梅毒感染状况与危险因素分析
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国家自然科学基金(81703273);江苏省自然科学基金(BK20171054);江苏高校优势学科建设工程基金;江苏高校品牌专业建设工程(PPZY2015A067)


Analysis of syphilis infection and influencing factors in a drug rehabilitation center in Jiangsu Province
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    摘要:

    目的:了解江苏省某强制隔离戒毒所男性戒毒人群的梅毒感染情况及其危险因素。方法:于2018年6—8月对江苏省某强制隔离戒毒所男性戒毒人群进行横断面调查,采用梅毒螺旋体颗粒凝集实验检测抗体,通过问卷调查基本信息、吸毒情况及性行为情况。结果:790例中共发现133例梅毒抗体阳性,梅毒感染率16.8%,梅毒组平均年龄(P < 0.001)与开始吸毒的平均年龄(P=0.002)高于非梅毒组,两组间性伴侣情况存在差异(P=0.044);多因素Logistic回归分析结果显示,吸毒年限较长(OR=1.04,95%CI:1.00~1.07)和有临时性伴侣(OR=1.90,95%CI:1.18~3.05)是该人群梅毒感染的危险因素。结论:该人群梅毒感染率高,与吸毒年限较长和不安全性行为有关。

    Abstract:

    Objective:To understand the infection status and risk factors of syphilis among male drug addicts in a compulsory isolation detoxification center in Jiangsu Province. Methods:A cross-sectional survey was conducted among male drug addicts in a compulsory isolation detoxification center in Jiangsu Province from June to August 2018. The antibodies were detected by the syphilis particle agglutination test,and the basic information,drug abuse and sexual behavior were investigated using a questionnaire. Results:Among 790 people,133 cases of syphilis antibody were found to be positive. The syphilis infection rate was 16.8%. The average age of syphilis group(P < 0.001)and the average age of starting drug use(P=0.002)were higher than those of non-syphilis group. There was a difference in sexual partner between the two groups(P=0.044);multivariate analysis showed that the average age of syphilis group(P < 0.001)and the average age of starting drug use(P=0.002)were higher than those of non-syphilis group. There was a difference in sexual partner between the two groups(P=0.044);multivariate analysis showed that longer years of drug use(OR=1.04,95% CI:1.00~1.07)and temporary sexual partners(OR=1.90,95%CI:1.18~3.05)were risk factors for syphilis infection in this population. Conclusion:The syphilis infection rate is high in this population. It is associated with longer years of drug use and unsafe sexual behavior.

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倪泽阳,叶翔宇,王一迪,黄 鹏,喻荣彬.江苏某戒毒所梅毒感染状况与危险因素分析[J].南京医科大学学报(自然科学版),2021,(7):1079-1083

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  • 收稿日期:2021-01-25
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  • 在线发布日期: 2021-07-25
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