Objective: To evaluate the influence of health education on the therapy effectiveness of chronic obstructive pulmonary disease(COPD) by evidence-based nursing. Methods: Correlative literature was searched from main medical database. Studies were brought into this research according to the inclusion and exclusion criteria. Meta-analysis was used in eight aspects including the numbers of treatment compliance,grade of SGRQ,pulmonary function test,mastery of knowledge,hospital days, number of admissions, treatment visits and six-minute of walk test. Results: It showed significant differences in numbers of treatment compliance,grade of SGRQ, pulmonary function test(FEV1/FVC%)and hospital days between the health education group and control group, but no significant differences in other aspects. Conclusion: The health education is good for the patients and their families to a certain extent. It is necessary to do further studies on health education for improvement.