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Study on relationship between perifollicular blood flow and in vitro fertilization-embryo transfer
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    Objective:To study the relationship between perifollicular blood flow and follicule development, oocyte maturing rate, fertilizing rate, cleaving rate, embryo quality and the outcomes of embryo transfer. Methods:The samples were selected from 66 suffers who underwent in vitro fertilization(IVF)or intracytoplasmic sperm injection(ICSI). Eeach patients perifollicular blood flow(diameter ≥12mm )was estimated on the day of human chorionic gonadotropin(HCG)administration. Results:Among 66 cycles,26(39.4%) cycles resulted in pregnancy. perifollicular blood flow resistance index(RI), peak systolic velocity/end diastasis velocity(S/D) of non-pregnant group was significantly higher than that of the pregnant group(P < 0.004). When RI<0.49, the pregnancy rates, fecundation rates, fertilization rates, metaphase numbers for the of second meiosis oocytes increased evidently(P < 0.05),but there were no statistical difference in gonadotropin dosage, cycle frequency, infertility years, ages, estradiol(E2)on the day of HCG administration, numbers of oocyet retrieved and high-quality embryo rates(P > 0.05). There were no statistical difference between non-pregnant group and pregnant group in S and D(P > 0.05). There was no correlation between periFollicular blood flow RI and follicular diameter by linear regression analysis. Conclusion:Our study shows that perifollicular blood flow RI and S/D are effective indices of predicting the pregnancy outcome of IVF-ET.

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Yan Zhang, Jing Yang, Wangming Xu.[J].南京医科大学学报(自然科学版),2008,28(1):57-60

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  • 收稿日期:2007-08-23
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