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Immunomodulation effects of heat-treated Enterococcus faecalis FK-23(FK-23) in mice
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This work was supported by Sino-Japanese Cooperation Projects(1738)

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    Objective:The purpose of this study was to evaluate the effects of Enterococcus faecalis FK-23(FK-23) on the immune function in mice. Methods:Mice were treated with three doses of the FK-23(0.05, 0.1, 0.2, 0.6 g/kg body weight) for 30 days. Delayed type hypersensitivity (DTH), monocyte phagocytic function, serum hemolysis antibody and natural killer cell activity were studied. Results:The significant increases in mice treated with 0.6 g/kg bw were found in DTH, phagocytic function of monocyte, serum hemolysis antibody and natural killer cell activity. Conclusion:The results from the present study suggest that FK-23 could improve both specific and non-specific immune function.

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Takashi Shimada, Yunqing Cai, Lei Cheng, Chie Motonaga, Kazutake Fukada, Yoshihisa Kitamura, Jieshu Wu.[J].南京医科大学学报(自然科学版),2009,29(3):173-176

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  • 收稿日期:2009-01-14
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