Multiple myeloma（MM）is an acquired hematologic malignancy with an unclear etiology. Imaging examinations are essential for MM detection. PET/CT，which combines metabolic and anatomical information，plays a crucial role in the diagnosis， treatment response evaluation，and prognosis prediction of MM. Currently，18F - FDG is the most widely used radiotracer for PET imaging. However，as a glucose analog，18F-FDG uptake lacks specificity，and its imaging can be easily affected by various factors. In recent years，research teams worldwide have been investigating novel PET tracers for MM to develop more specific imaging agents. This review article provides a comprehensive analysis of both conventional and emerging PET tracers in MM，aiming to help healthcare professionals understand the value and advances of PET imaging in this disease.