脊髓损伤后早期并发症最新治疗研究进展
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南京医科大学第一附属医院骨科,江苏 南京 210029

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R683.2

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江苏省人民医院高层次人才培育计划(第一期)(CZ0121002010039)


Research progress on the newest treatment of early complications after spinal cord injury
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Department of Orthopedics,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029 ,China

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    摘要:

    脊髓损伤(spinal cord injury,SCI)是一种严重的中枢神经系统疾病,具有极高的致残率和致死率,通常由外伤致脊柱爆裂骨折引起,常见原因包括交通事故、高处坠落和跌倒等。SCI后的患者会出现运动和感觉功能的缺失,并可能引发多种并发症,如呼吸功能障碍、心血管功能障碍、病理性疼痛、肌肉痉挛、神经源性膀胱以及肠道功能障碍等,不仅给患者带来极大的身心痛苦,还严重影响其生活质量和预后。早期手术干预可能挽救部分神经功能,而康复训练也是不可或缺的治疗手段。 SCI的并发症管理需要多学科团队的密切协作,有效的预防和治疗措施能够显著减轻患者的痛苦,并延长其生存期。文章综述了SCI早期并发症的最新研究进展,旨在为临床医生提供参考,以优化患者的治疗方案,改善生活质量。

    Abstract:

    Spinal cord injury(SCI)is a severe central nervous system disorder with a high rate of disability and mortality. It is typically caused by traumatic vertebral burst fractures,resulting from incidents such as traffic accidents,falls from a height,or slips. After injury,patients often experience loss of motor and sensory functions,along with various complications,including respiratory dysfunction,cardiovascular disorders,pathological pain,muscle spasms,neurogenic bladder,and gastrointestinal dysfunction. These complications not only cause significant physical and psychological distress but also severely impair patients’quality of life and longterm prognosis. Early surgical intervention may partially salvage neural function,while rehabilitation training is also the essential therapeutic approach. The management of complications requires close collaboration among multidisciplinary teams. Effective preventive and therapeutic measures can significantly alleviate pain of patients and prolong survival. This review summarizes the latest research progress on early complications of SCI,aiming to provide references for clinicians to optimize treatment plans and improve the quality of life for patients.

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葛同飞,李文博,凡进.脊髓损伤后早期并发症最新治疗研究进展[J].南京医科大学学报(自然科学版),2025,45(9):1352-1361

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  • 在线发布日期: 2025-09-11
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