文章摘要
陆如纲,易 军,刘继炎,张儒仿.经肛门手术与传统剖腹手术对巨结肠患儿术后应激反应的对比研究[J].南京医科大学学报,2007,(7):751~753
经肛门手术与传统剖腹手术对巨结肠患儿术后应激反应的对比研究
Comparison of laparotomy and transanal pull-through operation for the surgical stress in the treatment of Hischsprung?蒺s disease
投稿时间:2007-01-08  
DOI:10.7655
中文关键词: 巨结肠  先天性  白细胞介素-6  C反应蛋白  儿童
英文关键词: megocolon  congenital  interleukin-6  C-reaction protein  children
基金项目:南京医科大学科技发展基金资助项目(NY0570)
作者单位
陆如纲 南京医科大学附属南京儿童医院普外科,1心胸外科,江苏 南京 210008 
易 军 南京医科大学附属南京儿童医院普外科,1心胸外科,江苏 南京 210008 
刘继炎 南京医科大学附属南京儿童医院普外科,1心胸外科,江苏 南京 210008 
张儒仿 南京医科大学附属南京儿童医院心胸外科,江苏 南京 210008 
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中文摘要:
      探讨经肛门巨结肠根治术与传统剖腹手术对先天性巨结肠患儿手术创伤程度的差别?方法:30例患儿随机分为经肛门组及剖腹手术组各15例?每例患儿于术前24 h?术后24 h?72 h清晨空腹抽取静脉血,用ELISA法测量血清中IL-6的浓度,应用速率散射比浊法测量C反应蛋白的浓度,并对检测结果进行统计学处理?结果:两组患儿术后白细胞介素-6(IL-6)及C反应蛋白均较术前有明显变化(P < 0.05)?经肛门组IL-6?C反应蛋白浓度在术后24 h及72 h均较剖腹组要低(P < 0.05)?结论:经肛门巨结肠根治术较传统剖腹手术对先天性巨结肠患儿所造成的手术创伤程度要小?
英文摘要:
       Objective:To make a comprasion in surgical stress between laparotomy and transanal pull-throug operation on Hischs-prung?蒺s disease(HD) in children. Methods:Thirty patients were randomly divided into laparotomy group(n=15) and transanal pull-through group(n=15). The blood was collected in the morning before operation, 24 and 72 h postoperation. Plasma levels of IL-6 were determined by ELISA,and C-reaction protein(CRP) levels were measured by immune rate nephelometry. Methods:The statistical difference before and after surgery was analyzed by SPSS software. Results:There were significant difference in plasma levels of IL-6 and CRP before and after surgery(P < 0.05). The transanal pull-through group showed lower level of IL-6 and CRP on 24 and 72 h postoperation than laparotomy group(P < 0.05). Conclusion:Transanal pull-through operation causes less surgical stress than laparotomy on HD.
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