文章摘要
钟运健,艾小平,郑松波.运动和灌胃左旋肉碱?大豆肽对肥胖大鼠载脂蛋白的影响[J].南京医科大学学报,2007,(8):852~855
运动和灌胃左旋肉碱?大豆肽对肥胖大鼠载脂蛋白的影响
Effects of aerobic sports and supplement L-carnitine,the soybean petide to obesity rat
投稿时间:2007-01-08  
DOI:10.7655
中文关键词: 肥胖大鼠  载脂蛋白A  载脂蛋白B  左旋肉碱  大豆肽
英文关键词: aerobic  apoA  apoB  L-carnitine  soy peptide
基金项目:
作者单位
钟运健 南昌大学教育学院体育系,江西 南昌 330031 
艾小平 南昌大学教育学院体育系,江西 南昌 330031 
郑松波 江西师范大学体育学院,江西 南昌 330047 
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中文摘要:
       目的:研究有氧运动和灌胃左旋肉碱?大豆肽混合溶液6周对单纯性肥胖大鼠Lee’s指数及载脂蛋白的影响?方法:以通过建模成功后的SD肥胖大鼠为研究对象,通过6周跑台训练和每日灌胃10%的营养液[600 mg/(kg·d)左旋肉碱和15 mg/(kg·d)大豆肽],肥胖对照组每只灌胃2 ml/d蒸馏水?观察肥胖大鼠的体重?体长,计算Lee’s指数,检测实验大鼠体重?体长?载脂蛋白浓度等指标?结果:实验结束后,单纯运动干预组?单纯营养干预组和运动+营养干预组的Lee’s 指数明显低于肥胖对照组,两者比较差异均有显著性(P < 0.05),但3个实验组之间无差异(P > 0.05);营养干预?运动干预组?运动+营养干预都明显地降低了apoB的水平(P < 0.05);单纯运动干预和单纯营养干预对肥胖大鼠的apoA影响均没有显著性变化(P > 0.05),而运动+营养干预对肥胖大鼠apoA的影响差异有显著性(P < 0.05)?结论:通过8周喂养高脂高糖饲料成功建立了肥胖大鼠模型?运动与营养干预能改善脂质代谢,显著降低肥胖大鼠apoB浓度,升高apoA浓度?
英文摘要:
      Objective:To investigate the effects of the aerobic sports and supplement L-carntine,the soybean petide to fat mouse among six weeks,analyze the influence about Lee?蒺s index and apoprotein. Methods:SD fat model mouse were taken as the reasearch object,they were taken a traning through 6 weeks and filled with the 10% nourishing everyday[600 mg/(kg·d) L-C and 15 mg/(kg·d)SP]. The control group were only fill with the distilled water 2 ml/d. The obesity rat’s body weight,the body long were observed,Lee?蒺s the index were calculated. Results:The obesity intervention group,nutrition intervention group and aerobic+nutrition intervention group-s Lee-s index obviously were lowerthan the obese comparison group,and have obvious difference(P < 0.05),but There was nodifference among the three experimental groups(P > 0.05); The nutrition intervention,the aerobic intervention group,the aerobic+ nutrition intervention are obviously reduced the apoB level(P < 0.05); The aerobic intervention and the nutrition intervene to the obesity rat-s apoA influence did not have the obvious change(P > 0.05),but the aerobic+ nutrition intervenes to the obesity rat-s apoA influence had obvious chang(P < 0.05). Conclusion:Through the nutrition feed 8 weeks,the obesity rat model were established sucessfully. The movement and the nutrition intervention can improve the lipin metabolism,remarkably reduce the obesity rat’s apoB density, and elevates the apoA density.
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