文章摘要
居 峰,王 骏,顾 兵,夏文颖.不动杆菌属5年耐药性监测结果分析[J].南京医科大学学报,2007,(10):1174~1176
不动杆菌属5年耐药性监测结果分析
A 5-year surveillance study of Acinetobacter species resistance
投稿时间:2007-03-30  
DOI:10.7655
中文关键词: 不动杆菌属  抗菌药物  耐药性监测
英文关键词: Acinetobacter  antimicrobial agents  surveillance of resistance
基金项目:
作者单位
居 峰 南京医科大学第一附属医院临床检验中心,江苏 南京 210029 
王 骏  
顾 兵  
夏文颖  
摘要点击次数: 1302
全文下载次数: 153
中文摘要:
      目的:了解不动杆菌属(包括鲍曼不动杆菌?醋酸钙不动杆菌等)的分离率,监测并分析其对临床常用抗菌药物的耐药性变化?方法:采用API鉴定系统鉴定细菌;K-B纸片扩散法测定抗菌药物敏感性;WHONET 5.4软件进行数据分析?结果:2002~2006年不动杆菌的临床分离率逐年上升,由2002年的3.3%上升至2006年的6.8%;不动杆菌对多种常用抗菌药物的耐药率有不同程度的上升,其中耐药率增幅较大的是:阿米卡星21.9%~59.6%?哌拉西林/他唑巴坦25.4%~54.6%?头孢他啶41.5%~69.1%?结论:不动杆菌对多种常用抗菌药物耐药率呈上升趋势,应加强监测;同时对于不动杆菌对阿米卡星?哌拉西林/他唑巴坦和头孢他啶等药物耐药率的快速增长应引起重视,合理选用抗菌药物?
英文摘要:
      Objective:To study the isolation rate of Acinetobacter species(including Acinetobacter baumannii and Acinetobacter calcoaceticus-baumannii),survey and analyze the changes of Acinetobacter resistance to common antimicrobial agents. Methods:The bacteria were identified by API system; the sensitivity of antimicrobial agents was tested by K-B method; the data was analyzed by WHONET 5.4. Results:The isolation rate of Acinetobacter was increasing year-by-year from 3.3% in 2002 to 6.8% in 2006; and the resistance rates of Acinetobacter to common antimicrobial agents was increasing. The three of the highest increase as follows:Amikacin from 21.9% to 59.6%,Piperacillin/tazpbactam from 25.4% to 54.6%,Ceftazidime from 41.5% to 69.1%. Conclusion:It’s important that surveillance data of the resistance rates of Acinetobacter to common antimicrobial agents,place importance on high increases of the resistance rates and select antimicrobial agents rational.
查看全文   查看/发表评论  下载PDF阅读器