文章摘要
孟光乾,朱成宾,雎桂玉,肖 磊.临床深部真菌感染分布的调查分析[J].南京医科大学学报,2008,28(10):1365~1368
临床深部真菌感染分布的调查分析
The distribution of clinical deep fungus infection:investigation and analysis
  
DOI:10.7655
中文关键词: 真菌感染  药敏试验  调查分析
英文关键词: Fungus infection,drug susceptibility test,investigation analysis
基金项目:
作者单位
孟光乾 南京医科大学附属南京第一医院感染管理科,江苏 南京 210006 
朱成宾  
雎桂玉  
肖 磊  
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中文摘要:
      目的:了解临床真菌感染的分布及耐药情况?方法:采用法国生物梅里埃公司ATB微生物鉴定仪?ID32C真菌鉴定板和科玛嘉念珠菌显色培养基进行真菌鉴定,ATB Fungus药敏板进行药敏试验?结果:临床真菌感染病原菌以白色念珠菌?热带念珠菌和光滑念珠菌为主;分布专科以呼吸科?心内科?ICU和传染科为主;真菌对两性霉素B和5-氟胞嘧啶的敏感性较高,对氟康唑的耐药性较高?结论:临床应及时送检疑似真菌感染的标本,合理使用抗真菌的药物,减少深部真菌感染的发生?
英文摘要:
       Objective:To investigate the distribution of clinical fungus infection and the analysis of antibiotic resistance. Methods:Fungi were identified with bioMérieux Inc’s ATB Expression microbe identification system,ID32C strip and CHROMagar chromogenic substrate. Drug susceptibility test was executed with ATB Fungus drug susceptibility plate. Results:Candida albicans,candida tropicalis and candida glabrata are the main microorganism at clinical fungal infections; and they are distributed mainly among respiratory ward,cardiovascular ward,intensive care unit and infective ward; fungi show drug susceptibility to amphotericin B and 5-flucytosin and drug resistance against fluconazole to some extent. Conclusion:Clinic suspect samples should be tested in time,and antifungal drugs should be applied on the basis of drug susceptibility test to minimize the incidents of deep fungal infections.
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