文章摘要
庄 静,胡建群,王剑翔,蔡晓峰.新型超声造影剂对肝纤维化-肝硬化定量诊断的研究[J].南京医科大学学报,2009,29(8):1164~1166
新型超声造影剂对肝纤维化-肝硬化定量诊断的研究
Study of new type of an ultrasound contrast agent in quantitative diagnosis of hepatic fibrosis and cirrhosis
投稿时间:2009-03-02  
DOI:10.7655
中文关键词: 肝纤维化  肝硬化  超声造影剂  HA-VTT
英文关键词: hepatic fibrosis  hepatic cirrhosis  ultrasound contrast agents  HA-VTT
基金项目:江苏省社会发展计划(BS2006075)
作者单位
庄 静 南京医科大学第一附属医院超声诊断科,江苏 南京 210029 
胡建群  
王剑翔  
蔡晓峰  
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中文摘要:
      目的:探讨新型超声造影剂对肝纤维化-肝硬化定量诊断的研究?方法:肝纤维化?肝硬化患者各20例,均经肝穿刺病理证实,正常对照组10例,无任何肝脏病史,采用实时灰阶超声造影,团注法注入声诺维(SonoVue),测定肝静脉到达时间(HVAT)及肝动脉到达时间(HAAT),两者相减得到肝动静脉渡越时间(HA-VTT)?结果:HA-VTT在正常对照组?肝纤维化组?肝硬化组间两两比较均有统计学意义(P < 0.05),肝硬化组HA-VTT较正常对照组明显缩短(P < 0.01)?结论:利用新型超声造影剂测量HA-VTT有望成为定量诊断肝纤维化?肝硬化的新方法?
英文摘要:
      Objective:To investigate the significance of contrast-enhanced ultrasound in quantitative diagnosis of liver fibrosis and cirrhosis. Methods:Twenty cases of liver fibrosis and 20 cases of liver cirrhosis proven by biopsy were enrolled in this study while 10 cases without liver disease history served as controls. A real time gray-scale contrast enhanced ultrasound was performed with SonoVue bolus injection to determine hepatic artery to vein transit time (HA-VTT). Results:There is a significant difference of the HA-VTT among the three groups(P < 0.05). HA-VTT in hepatic cirrhosis group was shorter than controls(P < 0.01). Conclusion:Determination of HA-VTT were considered to be a new diagnostic method in quantitative diagonosis of hepatic fibrosis and cirrhosis.
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