objective:to study the qualitative and quantitative methods of single herb in anti－virus oral liquid,and improve the quality standard of anti－virus oral liquid. Methods:on qualitative study,fructus forsythiae,rhizoma anemarrhenaeand and rhizoma acori tatarinowii were identified by thin－layer chromatography(tlc),and herba pogostemonis,radix rehmanniae were also studied. On quantitative study,the method of high performance liquid chromatography (hplc) for determination of phillyrin in anti－virus oral liquid was established. Results:rhizoma anemarrhenae,rhizoma acori tatarinowii and fructus forsythiae can be identified by tlc. The average recovery of phillyrin was 99.42%,rsd =1.75%. Conclusion:the method is simple,accurate and specific,and can be used for the quality control of anti－virus oral liquid.