文章摘要
王爱萍,蒋克春,王 伟,刘 超.血压和血糖与老年人不同死因的相关性[J].南京医科大学学报,2010,(5):692~696
血压和血糖与老年人不同死因的相关性
The relationship between blood pressure,blood glucose and the different causes of death in elderly
投稿时间:2009-12-02  
DOI:10.7655
中文关键词: 血压  血糖  死因  老年
英文关键词: blood pressure,blood  glucose,death  causes  elderly
基金项目:江苏省医学领军人才基金
作者单位
王爱萍 南京医科大学第一附属医院内分泌科,江苏 南京 210029 
蒋克春 解放军第454医院内分泌科,江苏 南京 210002 
王 伟 解放军第454医院内分泌科,江苏 南京 210002 
刘 超 南京医科大学第一附属医院内分泌科,江苏 南京 210029 
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中文摘要:
      目的:研究血压和血糖与老年人不同死因之间的关系,为临床预防提供指导方向?方法:在资料相对完整的死亡患者883例中,选择年龄>60岁的501例作为调查对象?其中,糖尿病人群180例,分为:糖尿病高血压组(DM/HT组,108例,占60.14%)和糖尿病非高血压组(DM组,72例,39.86%);非糖尿病人群321例,分为:非糖尿病高血压组(HT组,130例,40.50%)和非糖尿病非高血压组(非DM/HT组,191例,59.50%)?观察各组患者的性别?年龄?血压?血糖和死因(主要是指心脑血管意外?肿瘤?感染和尿毒症)?结果:① 老年人高血压患病率:非糖尿病40%,糖尿病60%,且男性好发;② DM/HT?HT脑出血是第一位死因,超过30%;DM?非DM/HT血管意外仅20%,且以梗塞性疾病为主;③ DM?非DM/HT恶性肿瘤是第一位死因;高血压与肿瘤无关(肾梭形细胞癌除外);④ 糖尿病2个亚组感染患病率高;⑤DM/HT组?HT组尿毒症患病率高于其余两组;⑥多元回归分析后,收缩血压?舒张血压与心脑血管意外相关,与肿瘤?感染无关,前者与尿毒症也有相关性;空腹血糖与4种死因均相关?结论:血压和血糖与老年人不同死因之间有相关性,应针对不同人群进行相应疾病预防?
英文摘要:
      Objective:To study the relationship between blood pressure,blood glucose and the different causes of death in elderly,and then provide a guidance for clinical prevention. Methods:883 dead patients with relatively complete information were investigated,to choose cases aged over 60 years as subjects. The 501 patients were divided into two groups:180 diabetics and 321 non-diabetics,and then were subgrouped according to blood pressure:diabetes/hypertension group(DM/HT,108 cases,60.14%),diabetes group(DM,72 cases,39.86%),hypertension group(HT,130 cases,40.50%),non diabetes/hypertension group(non-DM/HT,191 cases,59.50%) respectively. Sex,age,blood pressure,blood glucose and cause of death were observed in each group. Results:① The incidence of hypertension in the elderly were 40% in non-diabetes and 60% in diabetes,and higher in men;②Cerebral hemorrhage was the first cause of death(more than 30%) in DM/HT and HT groups;meanwhile vascular accident,mostly infarction was only 20% in DM and non-DM/HT groups;③Malignant tumors was the first cause of death in DM and non-DM/HT groups,and meanwhile it was not related with hypertension(except for renal spindle cell carcinoma);④There was a high prevalence of infection in the two sub-groups of diabetes;⑤The uremia prevalence was higher in DM/HT group and HT group than in the other two subgroups;⑥Multiple regression analysis showed systolic blood pressure and diastolic blood pressure were associated with cardio-cerebral vascular accident,unrelated to tumors and infection,the systolic blood pressure was also associated with uremia;fasting blood glucose were associated with the four causes of death. Conclusions:There was a relationship between blood pressure and blood glucose with the different causes of death in the elderly,and we should carry into disease prevention accordingly to different groups.
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