血压和血糖与老年人不同死因的相关性
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江苏省医学领军人才基金


The relationship between blood pressure,blood glucose and the different causes of death in elderly
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    摘要:

    目的:研究血压和血糖与老年人不同死因之间的关系,为临床预防提供指导方向-方法:在资料相对完整的死亡患者883例中,选择年龄>60岁的501例作为调查对象-其中,糖尿病人群180例,分为:糖尿病高血压组(DM/HT组,108例,占60.14%)和糖尿病非高血压组(DM组,72例,39.86%);非糖尿病人群321例,分为:非糖尿病高血压组(HT组,130例,40.50%)和非糖尿病非高血压组(非DM/HT组,191例,59.50%)-观察各组患者的性别-年龄-血压-血糖和死因(主要是指心脑血管意外-肿瘤-感染和尿毒症)-结果:① 老年人高血压患病率:非糖尿病40%,糖尿病60%,且男性好发;② DM/HT-HT脑出血是第一位死因,超过30%;DM-非DM/HT血管意外仅20%,且以梗塞性疾病为主;③ DM-非DM/HT恶性肿瘤是第一位死因;高血压与肿瘤无关(肾梭形细胞癌除外);④ 糖尿病2个亚组感染患病率高;⑤DM/HT组-HT组尿毒症患病率高于其余两组;⑥多元回归分析后,收缩血压-舒张血压与心脑血管意外相关,与肿瘤-感染无关,前者与尿毒症也有相关性;空腹血糖与4种死因均相关-结论:血压和血糖与老年人不同死因之间有相关性,应针对不同人群进行相应疾病预防-

    Abstract:

    Objective:To study the relationship between blood pressure,blood glucose and the different causes of death in elderly,and then provide a guidance for clinical prevention. Methods:883 dead patients with relatively complete information were investigated,to choose cases aged over 60 years as subjects. The 501 patients were divided into two groups:180 diabetics and 321 non-diabetics,and then were subgrouped according to blood pressure:diabetes/hypertension group(DM/HT,108 cases,60.14%),diabetes group(DM,72 cases,39.86%),hypertension group(HT,130 cases,40.50%),non diabetes/hypertension group(non-DM/HT,191 cases,59.50%) respectively. Sex,age,blood pressure,blood glucose and cause of death were observed in each group. Results:① The incidence of hypertension in the elderly were 40% in non-diabetes and 60% in diabetes,and higher in men;②Cerebral hemorrhage was the first cause of death(more than 30%) in DM/HT and HT groups;meanwhile vascular accident,mostly infarction was only 20% in DM and non-DM/HT groups;③Malignant tumors was the first cause of death in DM and non-DM/HT groups,and meanwhile it was not related with hypertension(except for renal spindle cell carcinoma);④There was a high prevalence of infection in the two sub-groups of diabetes;⑤The uremia prevalence was higher in DM/HT group and HT group than in the other two subgroups;⑥Multiple regression analysis showed systolic blood pressure and diastolic blood pressure were associated with cardio-cerebral vascular accident,unrelated to tumors and infection,the systolic blood pressure was also associated with uremia;fasting blood glucose were associated with the four causes of death. Conclusions:There was a relationship between blood pressure and blood glucose with the different causes of death in the elderly,and we should carry into disease prevention accordingly to different groups.

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王爱萍,蒋克春,王 伟,刘 超.血压和血糖与老年人不同死因的相关性[J].南京医科大学学报(自然科学版),2010,(5):692-696

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  • 收稿日期:2009-12-02
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