文章摘要
卜丽娜,许 岚,吴鹏西.良恶性甲状腺结节超声造影定量分析[J].南京医科大学学报,2010,(11):1636~1640
良恶性甲状腺结节超声造影定量分析
Quantitative analysis of contrast-enhanced ultrasonography about benign and malignant thyroid nodules
投稿时间:2010-05-11  
DOI:10.7655
中文关键词: 甲状腺结节  超声造影  时间-强度曲线
英文关键词: thyroid nodules  contrast-enhanced ultrasonography  time-intensity curve(TIC)
基金项目:南京医科大学科技发展基金重点项目(2005NYD2D36)
作者单位
卜丽娜 南京医科大学附属无锡市人民医院内分泌科,江苏 无锡 214000 
许 岚 南京医科大学附属无锡市人民医院内分泌科,江苏 无锡 214000 
吴鹏西 南京医科大学附属无锡市人民医院内分泌科,江苏 无锡 214000 
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中文摘要:
      目的:超声造影定量分析良恶性甲状腺结节的规律?方法:对64例拟手术治疗的甲状腺结节患者行超声造影检查,制备时间-强度曲线(TIC),根据术后病理结果分组进行TIC定量分析?结果:①常规超声联合超声造影诊断与病理的符合率为98.44%;②TIC形态特征:乳头状癌多呈“快进-慢出”,良性结节(包括结节性甲状腺肿和腺瘤)多呈“同进-慢出”;③TIC定量参数特征:乳头状癌呈“快进-等强-慢出”,结节性甲状腺肿呈“同进-低强-慢出”,腺瘤呈“同进-等强-慢出”?造影剂廓清速度乳头状癌<腺瘤(P < 0.05),乳头状癌<良性结节(P < 0.01)?结论:甲状腺超声造影TIC定量分析对于诊断和鉴别诊断甲状腺乳头状癌?结节性甲状腺肿?甲状腺腺瘤具有一定的意义,有着良好的应用前景?
英文摘要:
      Objective: To explore the value of quantitative analysis of contrast-enhanced ultrasonography for diagnosis and differential diagnosis of benign and malignant thyroid nodules. Methods: Sixty-four patients with thyroid nodules who had surgery in our hospital were selected to take contrast-enhanced ultrasonography,and then time-intensity curve(TIC) of contrast-enhanced ultrasonography was analyzed by computer software. Results:①These thyroid diseases which were diagnosed by conventional ultrasound and contrast-enhanced ultrasonography were highly consistent with the pathology results. ②The features of TIC: Most of papillary thyroid carcinomas were “quickly in and slowly out”, most of benign thyroid nodules (including nodular goiters and adenomas) were “simultaneously in and slowly out”. ③Features of quantitative parameters about TIC: The papillary thyroid carcinoma showed “more quickly in, the same intensity and more slowly out”; the nodular goiter showed “simultaneously in, lower intensity and more slowly out”; the adenoma showed “simultaneously in, the same intensity and more slowly out”. The speed of contrast excretion:The papillary carcinoma group was significantly slower than the adenoma group(P < 0.05); the papillary carcinoma group was significantly slower than the benign lesions(P < 0.01). Conclusion: Quantitative analysis of contrast-enhanced ultrasonography is useful in the diagnosis and differential diagnosis of papillary thyroid carcinoma and benign thyroid nodules, and has a good prospect.
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