Objective:To explore the relationship between carotid intima-media thickness(CIMT) and impaired glucose tolerance(IGT). Methods:One hundred and fifty subjects in IGI group and 130 controls were included. IMT and diameter of bilateral common carotid artery were measured by ultrasound automatically. Some biochemical parameters were measured simultaneously. Results:BMI,FPG,2-hPG,TC,LDL-C,TG and the average CIMT of IGT group were higher than that of control group(P < 0.01). There was no significant difference in sex,age,HDL-C,diameter and CIMT on righ and left sides between two groups(P > 0.05). Conclusion:CIMT increased in people with IGT remarkably, which implies that the onset of atherosderotic lesion in them.