文章摘要
刘 坤,孟峻嵩,王 勇,庄海军,徐宗源,傅广波,王云炎,王功成,刘 靓.2型糖尿病和高血压对血清前列腺特异抗原的影响[J].南京医科大学学报,2011,(7):1050~1052
2型糖尿病和高血压对血清前列腺特异抗原的影响
The changes of serum prostate specific antigen levels in type 2 diabetes and hypertension patients
投稿时间:2011-01-02  
DOI:10.7655
中文关键词: 前列腺特异抗原  糖尿病  高血压
英文关键词: prostate-specific antigen  diabetes  hypertension
基金项目:
作者单位
刘 坤 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
孟峻嵩 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
王 勇 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
庄海军 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
徐宗源 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
傅广波 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
王云炎 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
王功成 南京医科大学附属淮安第一医院泌尿外科,江苏 淮安 223300 
刘 靓 淮安市疾病预防控制中心,江苏 淮安 223301 
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中文摘要:
      目的:观察2型糖尿病?高血压和血清前列腺特异抗原(PSA)之间的关系?方法:将2005~2010年在门诊和住院患者中大于40岁的男性分为糖尿病组(n=71)?高血压组(n=163)和对照组(n=378),分别填写调查表并进行血清PSA检测,对统计结果进行分析?结果:糖尿病组血清PSA水平低于对照组血清PSA,差异具有统计学意义(P < 0.05);高血压组血清PSA水平略高于对照组血清PSA,差异无统计学意义(P > 0.05)?结论:糖尿病患者血清PSA水平低于正常人群,应防止低PSA导致前列腺癌漏诊的发生?
英文摘要:
      Objective:To evaluate the changes of serum prostate specific antigen(PSA) levels in type 2 diabetes and hypertension patients. Methods:Totally 612 patients from 40 to 78 years old were divided into three groups: diabetes group, hypertension group and control group. All the patients were invited to complete a questionnaire and serum PSA test. Then a two-way ANOVA was performed to examine the association of type 2 diabetes, hypertension and PSA. Results:The serum PSA level of diabetes group was lower than that of control group and there was statistically significant difference between them(P < 0.05). The serum PSA level of hypertension group was higher than that of control group. But the difference between the two groups wasn’t statistically significant(P > 0.05). Conclusion:Our results suggest that the patients with type 2 diabetes experience lower serum PSA levels comparing with those without diabetes. Further research is needed to elucidate whether the difference results in a relatively lower less cancer detection among diabetic men.
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