Objective:To analyze the survival rate of AIDS patients who initially received anti-retroviral therapy in 2005-2008 by the end of 2011,and to determine factors associated with survival status. Methods:Information of AIDS patients initially starting anti-retroviral therapy during 2005-2008 was collected from Chinese HIV/AIDS Integrated Control System. Kaplan-Meier was applied to make survival curve;and Cox proportional hazard regression model was used to determine associated factors of survival status. Results:Totally 451 cases were analyzed. The gender ratio of man to women was 1.75∶1. Most of participants were married or cohabitated,with 20 to 50 years old. The major transmitted route was heterosexual. Most of participants were from southern area of Jiangsu. At baseline,average CD4+ T cell counts were 107/mm3. Accumulative survival rates in 12th,24th,36th,48th and 60th after therapy were 0.88,0.85,0.84,0.78 and 0.78 respectively. 53.6% of participants died within the first six months of therapy. CD4+ T cell counts at baseline,initial therapy schedule,and therapy schedule changed were found to be associated with survival time of patients. Conclusion:Anti-retroviral therapy improved the survival rate of AIDS patients. Starting therapy earlier can get better treatment result.