文章摘要
杨传坤,徐 青,胡海洋,徐晓琴,丁 萍,李建军,傅更锋,还锡萍,羊海涛.江苏省HIV 阳性的MSM人群梅毒和 HSV-2 感染及影响因素分析[J].南京医科大学学报,2013,(5):672~675
江苏省HIV 阳性的MSM人群梅毒和 HSV-2 感染及影响因素分析
Prevalence and predictors of syphilis and herpes simplex type 2 virus (HSV- 2) infections among HIV-infected men who have sex with men in Jiangsu province
投稿时间:2012-12-17  
DOI:10.7655/NYDXBNS20130523
中文关键词: 男男性行为者  艾滋病  梅毒  单纯疱疹病毒Ⅱ型
英文关键词: men who have sex with men (MSM)  AIDS  active syphilis  HSV-2
基金项目:江苏省医学重点人才项目(RC2011087,RC2011086);江苏预防医学课题(Y201029)
作者单位
杨传坤 东南大学公共卫生学院流行病与卫生统计学系,江苏 南京 210009 
徐 青 东南大学公共卫生学院流行病与卫生统计学系,江苏 南京 210009 
胡海洋 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
徐晓琴 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
丁 萍 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
李建军 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
傅更锋 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
还锡萍 江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
羊海涛 东南大学公共卫生学院流行病与卫生统计学系,江苏 南京 210009
江苏省疾病预防控制中心性病艾滋病防制科,江苏 南京 210009 
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中文摘要:
      目的:了解江苏省男男性行为人群(men who have sex with men,MSM)中人类免疫缺陷病毒(human immunodd-ficiency virus,HIV)感染者的梅毒及单纯疱疹病毒Ⅱ型(herpes simplex virus 2,HSV-2)的感染情况及影响因素。 方法:2012年3~6月在南京?镇江市整群抽取HIV阳性的MSM 264例,对其进行随访问卷调查,并回顾其病例报告时的问卷信息。静脉血采集进行梅毒和HSV-2检测。结果:264例MSM中梅毒感染率为29.55% (78/264),其中现症梅毒感染率为 13.64%(36/264),HSV-2型特异性IgG抗体阳性率为28.03%(74/264)。多因素 Logistic 回归分析结果显示与现症梅毒感染有统计学意义的因素为感染前6个月内同性性伴数> 3人?HSV-2阳性;与HSV-2感染有统计学意义的因素为年龄> 35岁?本县区户籍?现症梅毒感染和接受安全套发放服务。结论:应探索新的干预模式和检测策略,以应对梅毒和HSV-2在MSM人群中的传播和流行。
英文摘要:
      Objective:To analyze the prevalence and predictors of syphilis and herpes simplex type 2 virus (HSV-2) infections among HIV-infected men who have sex with men(MSM) in Jiangsu province. Methods:MSM were convened with Cluster sampling and investigated with follow-up questionnaire survey. We reviewed the case reports of their questionnaire information in Nanjing and Zhenjiang city from March to June,2012. Blood samples were collected to detect syphilis and HSV-2 infections. Results:Total of 264 HIV-infected MSM enrolled in the interview and blood sampling. The prevalence of syphilis and HSV-2 infections was 13.64% (36/264) and 28.03% (74/264),respectively. Multivariate logistic regression analysis showed that active syphilis infection was associated with having more than 3 sex partners in the latest 6 months and HSV-2 infection. The HSV-2 infection was associated with age > 35 years old,locality census register,recent syphilis infection and accepting condom issue service. Conclusion:The HIV-infected MSM in Jiangsu province had high infection rates of syphilis and HSV-2. It is necessary to further strengthen and implement and explore new intervention and testing methods.
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