文章摘要
相三婷,林红军,施海斌.2型糖尿病下肢动脉病变的超声应用及相关危险因素分析[J].南京医科大学学报,2014,(10):1382~1385
2型糖尿病下肢动脉病变的超声应用及相关危险因素分析
Applications of color Doppler ultrasound and related risk factors in lower extremity arterial disease of patients with type 2 diabetes
投稿时间:2014-05-26  
DOI:10.7655/NYDXBNS20141023
中文关键词: 2型糖尿病  下肢动脉  超声检查  危险因素
英文关键词: type 2 diabetes  lower extremity artery  ultrasonography  risk factors
基金项目:江苏省科技计划项目(SBE200970427)
作者单位
相三婷 南京医科大学附属江宁医院功能科,江苏 南京 211100南京医科大学第一附属医院超声诊断科,江苏 南京 210029 
林红军 南京医科大学第一附属医院超声诊断科,江苏 南京 210029 
施海斌 南京医科大学第一附属医院放射科,江苏 南京 210029 
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中文摘要:
      目的:探讨2型糖尿病(T2DM)患者下肢病变的发病率及危险性因素?方法:实验组T2DM患者95例与对照组健康体检患者53例接受彩色多普勒超声检查,比较两组的下肢动脉病变发生率及发生特点;依据有无下肢血管病变再将T2DM组分为2组,分析2组的临床资料及生化指标?结果:T2DM下肢动脉内中膜增厚?斑块?狭窄及闭塞发生率均明显高于对照组,狭窄多发生于膝以下血管;收缩压(SBP)?体质指数(BMI)?餐后2 h血糖(2hPG)?糖化血红蛋白(HbA1c)?高密度脂蛋白胆固醇(HDL-C)及总胆固醇(TC)与T2DM下肢动脉发病有关,其中SBP?BMI?2hPG?TC是T2DM下肢动脉发病的独立危险因素?结论:T2DM患者下肢动脉发病率高,应用超声检查可早期发现病变,同时积极监测SBP?BMI?2hPG?HbA1c?HDL-C以及TC等相关因素以了解病情的发生与发展?
英文摘要:
      Objective:To analyze the incidence and risk factors of lower extremity disease in patients with type 2 diabetes mellitus(T2DM). Methods:The experimental group of 95 patients with T2DM and the healthy control group of 53 patients were examined by color Doppler ultrasonography, the incidence rate and characteristics of lower extremity arterial disease of the two groups were compared. According to the presence or absence of lower extremity vascular disease,T2DM were divided into two groups,and then clinical data and biochemical indexes of two groups were analyzed. Results:The rates of intima-media thickness,plaque,stenosis and occlusion of lower limb artery in T2DM were significantly higher than those in the control group,stenosis occurred in the below knee vascular; systolic blood pressure(SBP), body mass index(BMI), two hour postprandial blood glucose(2hPG), glycosylated hemoglobin(HbA1c), high density lipoprotein cholesterol (HDL-C) and total cholesterol (TC) were closely correlated to the pathogenesis of T2DM lower extremity artery. SBP,BMI,2hPG and TC were independent risk factors for T2DM in lower extremity arterial disease. Conclusion:The incidence rate of lower limb arterial disease with T2DM patients is high. Ultrasound can early detect the disease, and actively monitor the related factors of SBP,BMI,2hPG,HbA1c,HDL-C and TC for the control of the occurrence and development of the disease.
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