ABVS和HHUS鉴别诊断良恶性乳腺肿瘤的meta分析
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江苏省卫生计生委项目(H201534)


Diagnostic accuracy of ABVS versus HHUS for benign and malignant lesions in breasts:a meta-analysis
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    摘要:

    目的:运用Meta分析评价自动乳腺全容积成像系统(automated breast volume scanning,ABVS)与手持探头超声(hand-held ultrasound,HHUS)对乳腺良-恶性肿瘤的诊断价值。方法:采用计算机自动配合手工检索COCHRANE-WEB OF SCIENCE-PUBMED-EMBASE-中文科技期刊全文数据库-中国生物医学文献数据库-中国知网(CNKI)-万方数字化期刊全文数据库(检索时间:建库至2015年3月7日),搜集并筛选出HHUS与ABVS鉴别诊断女性良恶性乳腺肿瘤的文献,应用STATA12.0软件对入选文献的试验数据进行分析。结果:17篇文献符合纳入标准。ABVS 和 HHUS合并诊断比值比分别为95.21(53.85~168.36)- 28.88(16.15~51.66),合并特异度分别为0.90(0.86~0.93)-0.84(0.78~0.89),合并敏感度分别为0.91(0.88~0.93)-0.84(0.79~0.88)。结论:ABVS在乳腺良-恶性肿瘤鉴别诊断方面较HHUS具有更高的临床价值。

    Abstract:

    Objective:To assess the diagnostic value of automated breast volume scanning (ABVS) versus hand-held ultrasound(HHUS) in benign and malignant breast tumor by meta-analysis. Methods: The Cochrane Library,Web of Science,the PubMed,EMBASE,VIP,CBM,CNKI and Wanfang databases (From date of creating database to 2015/03/07) were searched for studies on the diagnosis of breast cancer with ABVS and HHUS according to inclusion criteria,and then STATA12.0 software was performed to analyze the selected documents. Results: A total of 17 studies were included after screening. The pooled diagnostic odds ratio, specificity and sensitivity of ABVS and HHUS were 95.21 (53.85-168.36)and 28.88 (16.15-51.66), 0.90 (0.86-0.93) and 0.84(0.78-0.89), 0.91(0.88-0.93)and 0.84(0.79-0.88), respectively. Conclusion:The results of meta-analysis suggest that ABVS has higher value than HHUS in the diagnosis of benign and malignant breast tumor.

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王颖彦,宣 杨,张炽敏,李 嘉,王莉娜,李 岭,王 玲,史进军,高亚琴. ABVS和HHUS鉴别诊断良恶性乳腺肿瘤的meta分析[J].南京医科大学学报(自然科学版),2015,(11):1637-1642

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  • 收稿日期:2015-04-30
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  • 在线发布日期: 2015-11-30
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