文章摘要
季 玲,胡文志,吴红平,雍永宏,姚 静,许 迪.斑点追踪成像技术对肥厚型心肌病患者左心室心肌收缩同步性的评价[J].南京医科大学学报,2015,(12):1710~1713
斑点追踪成像技术对肥厚型心肌病患者左心室心肌收缩同步性的评价
Evaluation of left ventricular myocardial systolic dyssynchrony in hypertrophic cardiomyopathy using ultrasound speckle tracking imaging
投稿时间:2015-06-27  
DOI:10.7655/NYDXBNS20151208
中文关键词: 超声心动描记术  肥厚型心肌病  同步性
英文关键词: echocardiography  hypertrophic cardiomyopathy  dyssynchrony
基金项目:国家自然科学基金面上项目(81370280)
作者单位
季 玲 南京医科大学第一附属医院心脏科,江苏 南京 210029 
胡文志 南京医科大学第一附属医院心脏科,江苏 南京 210029 
吴红平 南京医科大学第一附属医院心脏科,江苏 南京 210029 
雍永宏 南京医科大学第一附属医院心脏科,江苏 南京 210029 
姚 静 南京医科大学第一附属医院心脏科,江苏 南京 210029 
许 迪 南京医科大学第一附属医院心脏科,江苏 南京 210029 
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中文摘要:
      目的:应用斑点追踪成像技术研究正常人及肥厚型心肌病患者的左心室长轴纵向?短轴径向及圆周方向达峰值应变的时间,探讨肥厚型心肌病患者左心室收缩的同步性。方法:获取正常对照组(30例)?非对称型肥厚型心肌病组(35例)标准心尖四腔?三腔?两腔和短轴二尖瓣?乳头肌?心尖水平图像;分别测量和比较肥厚型心肌病组与正常对照组各节段的纵向?径向和圆周方向的收缩期达峰值应变的时间,并将所有时间与心率标化,得到标化的达峰时间。结果:正常组左室长轴纵向?短轴径向?圆周方向应变的标化达峰时间之间差异无统计学意义;与对照组比较,肥厚型心肌病组各节段纵向应变的标化达峰时间(Tl)在多数节段显著降低 (P < 0.05),不仅发生在心肌肥厚的室间隔,心肌厚度正常的节段也降低;短轴径向应变的标化达峰时间(Tr)?圆周应变的标化达峰时间(Tc)在部分节段也延迟,但纵向应变的标化达峰时间延迟更加明显。结论:斑点追踪成像技术能够较好评价肥厚型心肌病患者左室整体和局部的收缩同步性。
英文摘要:
      Objective:To evaluate left ventricular myocardial systolic dyssynchrony in the patients with hypertrophic cardiomyopathy(HCM)by ultrasound speckle tracking imaging. Methods:Myocardial imaging of 35 HCM patients (HCM group)and 30 healthy subjects(control group)was collected,and their regional time to peak systolic strain in longitudinal,radial,circumferential motion were measured respectively. The data was compared and analyzed between the two groups. Results: In control group,no significant difference was found in time to peak longitudinal,radial and circumferential strain. Compared to control group,time to peak longitudinal strain(Tl)was significantly delayed,not only in the hypertrophic segments,but also in the segments with normal thickness. Time to peak radial strain (Tr)and time to peak circumferential strain (Tc)was also delayed,but more severe delay was found in longitudinal direction. Conclusion:Ultrasound speckle tracking imaging can quantitatively evaluate the left ventricular myocardial systolic dyssynchrony.
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