文章摘要
燕兰云,吴 婷,王 蔚,杨家伟,沈飞飞,葛 颂,唐金荣.奥卡西平治疗耳鸣的临床初探[J].南京医科大学学报,2015,(12):1761~1763
奥卡西平治疗耳鸣的临床初探
Primary investigation of oxcarbazepine treatment for tinnitus
投稿时间:2015-04-29  
DOI:10.7655/NYDXBNS20151221
中文关键词: 奥卡西平  耳鸣  THI评分
英文关键词: oxcarbazepine  tinnitus  tinnitus handicap inventory
基金项目:江苏省自然科学基金(BK2001116);江苏省卫生厅医学重点人才项目(RC2011072)
作者单位
燕兰云 南京医科大学第一附属医院神经内科,江苏 南京 210029 
吴 婷 南京医科大学第一附属医院神经内科,江苏 南京 210029 
王 蔚 南京医科大学第一附属医院神经内科,江苏 南京 210029 
杨家伟 南京医科大学第一附属医院神经内科,江苏 南京 210029 
沈飞飞 南京医科大学第一附属医院神经内科,江苏 南京 210029 
葛 颂 南京医科大学第一附属医院神经内科,江苏 南京 210029 
唐金荣 南京医科大学第一附属医院神经内科,江苏 南京 210029 
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中文摘要:
      目的:探讨奥卡西平治疗耳鸣的临床应用价值。方法:临床收集20例不同程度的耳鸣患者,根据患者的耳鸣减轻程度,调整奥卡西平的剂量,在治疗前?治疗4周和8周时,分别进行耳鸣残疾量表评分(tinnitus handicap inventory,THI)。结果:18例患者耳鸣程度均有不同程度的好转,治疗前后的THI评分具有统计学差异。功能性评分和严重性评分的改变与THI评分的改变存在相关关系,而情感评分的改变与其无相关关系。结论:奥卡西平在耳鸣治疗中具有重要的临床应用价值。
英文摘要:
      Objective:To study the clinical practice value of oxcarbazepine for the tinnitus treatment. Methods:We have collected 20 patients with varying degrees of tinnitus and given different doses of oxcarbazepine depending on the alleviative degrees of tinnitus,and tinnitus handicap inventory (THI)was used to assess the effect after the treatment of 4 weeks and 8 weeks,respectively.Results:Eighteen patients with tinnitus all got improvement with different levels,the change scores of THI showed statistically difference between before and after the treatment of tinnitus. There were correlations between the change of functional scores and THI scores,as well as the severity scores and THI,however,there was no relations between changes of emotional scores and THI scores. Conclusion:Oxcarbazepine is worthy of clinical practice in the tinnitus treatment.
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