文章摘要
丁逸文,施海彬,孙良俊,陈奇峰,徐红豆,杨正强.冰水冷循环改变微波消融正圆率的实验研究[J].南京医科大学学报,2019,(4):581~584
冰水冷循环改变微波消融正圆率的实验研究
Experimental study on improving the spherical rate of microwave ablation by ice water cooled circulation
投稿时间:2018-11-05  
DOI:10.7655/NYDXBNS20190423
中文关键词: 微波消融  冰水冷却循环  类圆率
英文关键词: microwave ablation  ice water cooled cycle  spherical ratio
基金项目:国家自然科学基金(81571777)
作者单位
丁逸文 南京医科大学第一附属医院介入科江苏 南京 210029 
施海彬 南京医科大学第一附属医院介入科江苏 南京 210029 
孙良俊 南京亿高医疗器械有限公司江苏 南京 210000 
陈奇峰 中山大学附属肿瘤医院介入科广东 广州 510060 
徐红豆 南京医科大学第一附属医院介入科江苏 南京 210029 
杨正强 中国医学科学院肿瘤医院介入科北京 100021 
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中文摘要:
      目的:初步比较冰水循环微波消融与常温水循环微波消融对消融灶形态的影响。方法:取离体猪肝脏共9个,重4.5~5.2 kg。每块肝脏在不同位置用常温水及冰水循环同时进行消融。根据循环水不同分为冰水冷循环组及常温水冷循环组。实验在不同消融功率(40、60、80 W)下分别进行不同消融时间(5、8、10 min)各1次。消融结束后,沿针道切开肝脏,测量消融灶的纵径(LD)、横径(TD)、前冲径(PD),计算类圆率(SR)。结果:冰水组在纵径上较常温组分别相对缩短13%、10%、12%、15%、11%、13%、8%、8%,而横径及前冲径无明显变化,而冰水组在类圆率上分别相对提高22%、21%、7%、14%、1%、1%、11%、5%、4%;另外,在相同功率下,短消融时间(5 min)时类圆率改善相对明显;而在相同消融时间下,低功率(40 W)时类圆率改善相对明显。结论:本研究初步提示,冰水冷循环微波消融可能可以通过缩短消融灶纵径提高类圆率,改善消融区域形态,尤其是在低功率短时间的情况下效果可能更好,但仍需进一步实验获得更为准确的结果。
英文摘要:
      Objective:To compare the effect of ice water cooled cycle microwave ablation and normal temperature water cooled cycle ablation on the morphology of ablation area. Methods Nine pieces of fresh isolated porcine livers,weighing 4.5?5.2 kg. The experiment was divided into ice water cooled cycle group and nomral temperature water cooled cycle group. Each liver was ablated with normal temperature water cycle and ice water cooled cycle at the same time,at different ablation power(40,60,80 W),with different duration(5,8,10 min). After ablation,the liver tissues were cut along the needle path. The longitudinal diameters(LD),transverse diameters(TD) and preshoot diameters(PD) of the ablation areas were measured,and the spherical ratios(SR) were calculated. Results:Descriptive approach was used for preliminary reporting. Compared with the normal temperature group,the LD of the ice water group was relatively shortened by 13%,10%,12%,15%,11%,13%,8%,8%,while the TD and PD were not obviously changed,so the SR was relatively increased by 22%,21%,7%,14%,1%,1%,11%,5%,4%. In addition,at the same power,the improvement of SR was more obvious in short duration time(5 min). While at the same duration time,the improvement of SR was more obvious at low power(40 W). Conclusion:This experiment preliminarily hints that microwave ablation with ice water cold cycle may increase the SR by shortening the LD of the ablation area,especially in the case of low power and short time. But further experiments are needed to obtain more accurate results.
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