A localization system for multiple magnetic targets based on magnetic sensor scanning detection
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摘要:
目的：探讨基于3D可调制翻转角超长回波链回聚脉冲成像（three-dimensional modulated flip angles technique in refocusing imaging with extended echo train，3D-MATRIX）的压缩感知（compressed sensing，CS）技术在膝关节中的临床应用价值。方法：对26例患者的26个膝关节均采用CS-3D-MATRIX（CS-3D）和3D-MATRIX（传统3D）扫描。对两组图像的伪影（0~4）、锐利度（0~4）和图像综合质量（0~4）进行评分；分析两组膝关节图像中的软骨、肌肉、滑膜液、骨髓腔和前交叉韧带的信噪比（signal to noise ratio，SNR），骨髓腔-软骨、骨髓腔-滑膜液、软骨-肌肉、滑膜液-软骨、滑膜液-前交叉韧带的对比噪声比（contrast to noise ratio，CNR），并进行统计学分析。结果：两序列图像伪影和总体图像质量无明显差异，CS-3D图像锐利度略低于传统3D［（3.39±0.50）分 vs. （3.79±0.42）分，P=0.008］。与传统3D相比，除骨髓腔和前交叉韧带外，CS-3D获得的SNR均升高；CS-3D滑膜液-前交叉韧带、滑膜液与软骨的CNR显著提高，其他组织的CNR值略有升高但无统计学差异。CS-3D扫描时间较传统3D减少了46%。结论：与传统3D扫描序列相比，CS-3D-MATRIX序列的扫描时间缩短，但图像质量无明显差异。
Abstract:
Objective：A localization system for multiple magnetic targets based on magnetic sensor rotation detection was studied，which was aimed at realizing human multiple capsule endoscopy positioning and nano-magnetic drug testing. Methods：A three-axis tunneling magnetoresistive sensor was used to make a circular motion near the magnetic source. Three sets of magnetic signals were acquired and transferred by three-dimensional coordinates. The position of the permanent magnet was solved using a positioning algorithm. Results：Through the preparation of LabVIEW PC program，the trajectory of two magnetic target tracking and motion curve storage and playback were achieved. Conclusion：The detection system has the advantages of good real-time，high precision and low cost，it has the potential application value for the positioning of multiple capsules in the human body and the detection of nano-magnetic drugs.
