文章摘要
褚 明,丁祥伟,王俊宏,顾周山,施姣姣.老年房颤患者导管射频消融疗效及复发相关因素分析[J].南京医科大学学报,2020,(12):1796~1799
老年房颤患者导管射频消融疗效及复发相关因素分析
Efficacy of catheter ablation and facfors related to recurrence in elderly patients with atrial fibrillation
投稿时间:2020-07-13  
DOI:10.7655/NYDXBNS20201210
中文关键词: 老年  房颤  射频消融
英文关键词: elderly patients  atrial fibrillation  ablation
基金项目:江苏省卫生健康委员会课题(BJ17019)
作者单位
褚 明 南京医科大学第一附属医院心血管内科江苏 南京 210029 
丁祥伟 南京医科大学第一附属医院心血管内科江苏 南京 210029 
王俊宏 南京医科大学第一附属医院心血管内科江苏 南京 210029 
顾周山 南京医科大学第一附属医院心血管内科江苏 南京 210029 
施姣姣 南京医科大学第一附属医院心血管内科江苏 南京 210029 
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中文摘要:
      目的:研究老年房颤患者导管射频消融的疗效及复发相关因素。方法:收集2013年1月—2016年12月于南京医科大学第一附属医院行房颤导管射频消融,且年龄≥60岁患者的临床资料,分析手术疗效、安全性及复发的相关因素。结果:共入组482例患者,年龄(66.5±4.7)岁。其中,男297例(61.6%),女185例(38.4%),阵发性房颤239例(49.6%),持续性房颤243例(50.4%)。围术期共4例穿刺局部并发症,无严重并发症发生。随访(20.4±5.6)个月,共104例(21.6%)患者房颤复发。房颤复发组与未复发组在左心房大小、糖尿病、心衰、房颤患者卒中风险评估评分(CHA2DS2?VASc)积分等因素存在显著差异(P < 0.05),两组年龄、性别、高血压病等因素无显著差异。结论:导管射频消融治疗老年房颤患者安全有效,左心房增大、合并糖尿病、心衰等可能与复发相关。
英文摘要:
      Objective:This study aims to analyze the real?world data regarding the effect of catheter ablation and the factors related to recurrence after ablation in elderly patients with atrial fibrillation. Methods:Elderly patients(≥60 years old)with atrial fibrillation receiving catheter ablation from January 2013 to December 2016 in our center were enrolled in this study. Clinical data were collected to confirm efficacy,safety,and recurrence?related factors of atrial fibrillation. Results:A total of 482 patients were eligible and the mean age of them was (66.5±4.7) years old. The study group included 297 males(61.6%)and 185 females(38.4%). There were 239(49.6%)patients diagnosed with paroxysmal atrial fibrillation,and the remains were persistent atrial fibrillation. There were 4 cases of perioperative complication and all of them were relevant to the venipuncture. The mean follow?up was (20.4±5.6) months. During the follow up,a total of 104(21.6%)patients experienced recurrence. The recurrent group and non?recurrent group were significantly different in left atrial diameter,diabetes,heart failure and CHA2DS2?VASc score(P < 0.05). There were no significant differences in age,gender,hypertension and other factors between the two groups. Conclusion:Catheter ablation of atrial fibrillation is safe and effective in elderly patients. Enlarged left atrium,and some comorbidities may be associated with recurrence of atrial fibrillation.
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