文章摘要
朱许萍,李艳瑜,许 岚.肠道菌群与多囊卵巢综合征代谢异常关系研究进展[J].南京医科大学学报,2020,(12):1885~1889
肠道菌群与多囊卵巢综合征代谢异常关系研究进展
Study on the relationship between gut microbiota and abnormal metabolism of polycystic ovary syndrome
投稿时间:2020-03-13  
DOI:10.7655/NYDXBNS20201229
中文关键词: 多囊卵巢综合征  肠道菌群  高雄激素血症  糖脂代谢异常  分型
英文关键词: polycystic ovary syndrome  gut microbiota  hyperandrogenism  abnormal glucose and lipid metabolism  typing
基金项目:无锡市卫计委重大项目(Z201807)
作者单位
朱许萍 南京医科大学附属无锡人民医院内分泌科江苏 无锡 214023 
李艳瑜 南京医科大学附属无锡人民医院内分泌科江苏 无锡 214023 
许 岚 南京医科大学附属无锡人民医院内分泌科江苏 无锡 214023 
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中文摘要:
      在育龄期女性中,多囊卵巢综合征(polycystic ovary syndrome,PCOS)的患病率已高达5%~10%,临床异质性大,发病机制尚不明确,大多数研究认为PCOS是一种多基因调控、多因素诱导、兼有糖脂代谢异常与类固醇激素代谢异常的疾病。近年来,越来越多的专家提出PCOS可能存在不同分型。肠道菌群作为近年来研究的热点,其与糖脂代谢紊乱、类固醇激素代谢紊乱存在关联,肠道菌群与多囊卵巢综合征发病机制的关系研究显得尤为重要。文章就肠道菌群与多囊卵巢综合征可能存在的关系进行综述。
英文摘要:
      At present,the prevalence of polycystic ovary syndrome(PCOS)is as high as 5%~10% among women of childbearing age. PCOS is characterized by high clinical heterogeneity and unclear pathogenesis. Most studies suggest that PCOS is a multi?gene?regulated,multi?factor?induced disease with abnormal metabolism of glucose,lipid and steroid hormone. In recent years,more and more experts have proposed that PCOS may have different types. Gut microbiota,as a hot research topic in recent years,is associated with disorders of glucose,lipid and steroid hormone metabolism. The relationship between gut microbiota and the pathogenesis of polycystic ovary syndrome is particularly important. This article reviews the possible relationship between gut microbiota and polycystic ovary syndrome.
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