Reproductive Medicine was one of the integrative subjects, which developed rapidly in recent years. This subject was greatly hopeful in this century. Seven-year-system medical students were senior medical talents with master degree. Nanjing Medical Unicersity set up reprodutive medicine as a required course for them. Through utilizing mutlimedia courseware and PBL (problem based learning) method, considering timely supplement and renewal of related knowledges, emphasizing the training of thinking ability,research ability and humanity quality, a good teaching effect had been achieved.