文章摘要
Yingchun Li,Yingbin Ge,Jun Du,Rong Zhou,Jin Chen,Luo Gu.[J].南京医科大学学报,2005,19(2):
Actin phosphorylation correlates with actin sequestration in ATP-depleted abbit renal proximal tubules
  
DOI:10.7655
中文关键词: 
英文关键词: ATP-depletion  renal proximal tubule  actin  phosphorylation
基金项目:
Yingchun Li  Yingbin Ge  Jun Du  Rong Zhou  Jin Chen  Luo Gu
Department of Physiology, Nanjing Medical University, Nanjing 210029, China;Department of Physiology, Nanjing Medical University, Nanjing 210029, China;Department of Physiology, Nanjing Medical University, Nanjing 210029, China;Department of Life Science, Indiana State University, Terre Haute, IN47809, USA;Department of Physiology, Nanjing Medical University, Nanjing 210029, China;Department of Physiology, Nanjing Medical University, Nanjing 210029, China
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中文摘要:
      
英文摘要:
      Objective: To demonstrate the relationship between actin phosphorylation and actin sequestration in ATP-depleted rabbit renal proximal tubules. Methods: Using two-dimensional electrophoreses and Western blotting to analyze the phosphorylation state of the sequestered actin in rabbit renal proximal tubules. Results: The analytical result of the sequestered actin indicated that nearly half of the actin was phosphorylated on serine residue(s). Conclusion: Result suggested a close correlation between actin sequestration and actin phosphorylation in ATP-depleted rabbit renal proximal tubules.
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